Results 191 to 200 of about 191,709 (318)

Comparative effectiveness of adjunctive rifampicin versus gentamicin for prosthetic valve endocarditis due to <i>Staphylococcus aureus</i>. [PDF]

JAC Antimicrob Resist
Kitano T, Yoshida S.
europepmc   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, Volume 4, Issue 1, Page 82-93, February 2026.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 606-611, February 2026.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton, Nielka P. van Erp, Annenienke C. van de Ven, Janneke E. W. Walraven, Loek A. W. de Jong   +4 more
wiley   +1 more source

Method Validation of an Ultra-High-Performance Liquid Chromatography (UHPLC) for the Bioequivalence Study of Rifampicin. [PDF]

Acta Med Philipp
Diño AJD, Tolosa EN, Yabes AM, Quiming NS, Estole-Casanova LA, Cagayan MSFS, Jimeno CA.   +6 more
europepmc   +1 more source

Miliary Tuberculosis With Immune Thrombocytopenia in 50‐Year‐Old Ethiopian Woman: A Case Report and Brief Review of Literature

Clinical Case Reports, Volume 14, Issue 2, February 2026.
Diffuse petechiae and non‐palpable purpura (lower extremities below knee, admission photo). ABSTRACT Immune thrombocytopenia (ITP) is a rare but recognized hematologic complication of tuberculosis (TB), particularly miliary TB. We present a case of a 50‐year‐old female with severe thrombocytopenia and hemorrhagic manifestations secondary to miliary TB.
Hayatu Awel Abdela, Tamirat Godebo Woyimo, Ragasa Getachew Bayisa, Sisay Tagese Tafese   +3 more
wiley   +1 more source

Clinical characteristics of pregnant patients with rifampicin-resistant tuberculosis: a retrospective analysis. [PDF]

BMC Infect Dis
Luo N, Lai M, Tang S, Wu G, Chen H.
europepmc   +1 more source

A Case Report on Disseminated Mycobacterium avium Complex Infection in an Otherwise Healthy Individual—A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Disseminated Mycobacterium avium complex (MAC) infection can mimic tuberculosis (TB) in immunocompetent individuals, leading to diagnostic and therapeutic challenges. Clinicians should consider nontuberculous mycobacteria (NTM) in patients unresponsive to anti‐tubercular therapy (ATT), especially in endemic regions.
Abdulla Bin Hridoy, Shadman Newaz, Moontasir Ahmed, Jannat Ara Tina, Supritom Sarker, Anika Tabassum, Mohammad Zakaria Al‐Aziz, Md. Robed Amin   +7 more
wiley   +1 more source

Divergent transcriptional regulation of redox-homeostasis and permeability modulate rifampicin tolerance and sensitivity in Mycobacterium tuberculosis. [PDF]

Nat Commun
Sebastian J, Ma S, Rustad T, Bustad E, Thomas A, Singh S, Kumar P, Sherman D, Alland D.   +8 more
europepmc   +1 more source

Why a Mycobacterium Avium Infected Patient Showed a Positive Xpert MTB/RIF Result?

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT This article discusses whether a MAC‐infected patient with a positive Xpert MTB/RIF test has a co‐infection with Mycobacterium tuberculosis (MTB). The patient presented with chronic, indolent pulmonary patchy shadows on imaging but lacked typical symptoms. The MTB antigen‐specific interferon‐gamma enzyme‐linked immunospot assay (T‐SPOT.TB) was
Lei Chen, Min Tang, Qin Wang, Hongni Jiang   +3 more
wiley   +1 more source

Structural Mechanism for Rifampicin Inhibition of Bacterial RNA Polymerase

Cell, 2001
E. Campbell, N. Korzheva, A. Mustaev, K. Murakami, S. Nair, A. Goldfarb, S. Darst   +6 more
semanticscholar   +1 more source