Results 101 to 110 of about 3,000 (187)

Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana

Plant, Cell &Environment, Volume 49, Issue 9, Page 7168-7190, September 2026.
ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros, Asier Largo‐Gosens, Cristina Úbeda, Cristina Hernández‐Fernández, Alba Manga‐Robles, Diego Rebaque, Antonio Encina, Hugo Mélida   +7 more
wiley   +1 more source

Relay Approach: A Convergent Synthesis of Key Fragments en route to (+)‐Neosorangicin A

Chemistry – A European Journal, Volume 32, Issue 32, 24 August 2026.
A selective synthesis of three key fragments of the antibiotically active (+)‐neosorangicin A is reported, providing a foundation for its convergent total synthesis and proof of strategy via a relay approach. ABSTRACT Herein, we report the synthesis of the three key fragments of the macrolide antibiotic (+)‐neosorangicin A, a compound exhibiting potent
Marvin Wenninger, Maxim Munt, Le Chang, Rositsa Stoykova, Roberto Ojcius, Oliver Spieß, Dieter Schinzer   +6 more
wiley   +1 more source

Early Administration of Rifampicin Does Not Induce Increased Resistance in Septic Two-Stage Revision Knee and Hip Arthroplasty

Antibiotics
Background/Objectives: Periprosthetic joint infection (PJI) is a severe complication that follows arthroplasty and occurs in approximately 2% of all cases. One of several cornerstones of therapy is an optimized antibiotic regimen. Early administration of
Leonard Grünwald, Benedikt Paul Blersch, Bernd Fink   +2 more
doaj   +1 more source

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, Volume 13, Issue 43, 3 August 2026.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

Structural Modifications of Nonsteroidal Anti‐Inflammatory Drugs (NSAIDs): New Horizons in Antimicrobial Drug Discovery

Archiv der Pharmazie, Volume 359, Issue 8, August 2026.
This review provides a comprehensive analysis of the molecular modifications applied to NSAIDs to develop novel antimicrobial agents. By focusing on structural changes and their impact on biological activity, the study highlights innovative strategies to combat the global challenge of antimicrobial resistance.
Ebru Koçak Aslan, Ayşe Karagüzel, Miyase Gözde Gündüz   +2 more
wiley   +1 more source

Tuberculosis prevalence and rifampicin resistance among presumptive patients in Nasarawa State: A three-year retrospective study

One Health Bulletin
Objective: To investigate the prevalence and rifampicin resistance of tuberculosis among presumptive patients in Nasarawa state, Nigeria. Methods: Patient data collected from January 2019 to December 2021 were retrospectively computed from the register ...
Ibrahim Hassan Ikrama, Amadou Talfi Zakou, Ngolo Jebes Lamini, Celestine Osanga, Attari Nasara Dogara, Lambo Yamusa Wakili, Daniel Abah Augustine, Muhammad Maryam Hassan, Regina Aluku, Caleb Luka Kyari, Agbawu M Agbawu, Godwin Attah Obande, Aleruchi Chuku   +12 more
doaj   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2607-2623, August 2026.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

The Antimycobacterial Activity, Toxicity and Chemical Composition of South African Propolis

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
This study presents one of the largest geographically diverse propolis collections reported globally, comprising 109 samples sourced from eight provinces across South Africa. The novelty of this work lies in the fact that it presents the first investigation of South African propolis against M. tuberculosis.
Nyiko F. Mzimba, Efficient N. Ncube, Elliasu Y. Salifu, Alvaro Viljoen, Bhavna Gordhan, Bavesh Kana, Sandy van Vuuren   +6 more
wiley   +1 more source

Serine/threonine protein kinase mediates rifampicin resistance in Brucella melitensis through interacting with ribosomal protein RpsD and affecting antioxidant capacity

mSystems
Brucellosis, a zoonotic disease, has re-emerged in both humans and animals, causing significant economic losses globally. Recently, an increasing number of rifampicin-resistant Brucella strains have been isolated worldwide without detectable mutations in
Yaqin Yuan, Wenqing Ning, Junjie Chen, Jiquan Li, Tianqi Xue, Cuihong An, Lingling Mao, Guangzhi Zhang, Shizhong Zhou, Jiabo Ding, Xiaowen Yang, Jianqiang Ye   +11 more
doaj   +1 more source

Acute Febrile Illness With Triple Co‐Infection: A Case Report on the Diagnostic Challenges of Overlapping Febrile Illnesses

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 35‐year‐old female presented with 5 days of fever, fatigue, and myalgia during the post‐monsoon season at Damak Hospital, Jhapa, Nepal. Clinical examination revealed fever (102.7°F), tachycardia (110 bpm), and crackles in the right lower lung field.
Santosh Basyal, Rahul Parajuli, Dipendra Prasad Yadav, Shardul Bhattarai, Kritick Bhandari, Shrijana Basyal, Gul Zaman, Rohit Parajuli   +7 more
wiley   +1 more source