Results 91 to 100 of about 3,000 (187)

Undetected rifampicin-resistant tuberculosis associated with rpoB I491F and V170F mutations in Botswana: Diagnostic implications

Journal of Global Antimicrobial Resistance
Background: Undetected rifampicin resistance is a threat to global tuberculosis (TB) control efforts by delaying effective treatment. In different studies, non-canonical rpoB mutations outside the rifampicin resistance-determining region have been ...
Tuelo Mogashoa, Justice T. Ngom, Johannes Loubser, Kedumetse Seru, Tuduetso Molefi, One Stephen, Rosemary M. Musonda, Simani Gaseitsiwe, Robin M. Warren, Anzaan Dippenaar, Elizabeth M. Streicher, Sikhulile Moyo   +11 more
doaj   +1 more source

Altered Pharmacokinetics and Delayed Sputum Conversion in Tuberculosis Patients Co‐Infected With HIV

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background HIV co‐infection affects host responses and pharmacokinetics (PK) of tuberculosis (TB) treatment. This study assessed the PK of first‐line anti‐TB drugs and clinical outcomes in patients with and without HIV co‐infection. Methods In this prospective observational study, 61 adults with sputum‐positive pulmonary TB, either confirmed ...
Aung Pyae Phyo, Richard M. Hoglund, Makoto Saito, Sein Sein Thi, Lei Lei Swe, Palang Chotsiri, Htet Ko Ko Aung, Win Pa Pa Tun, Banyar Maung Maung, Chanapat Pateekham, Wanitda Watthanaworawit, Gornpan Gornsawun, Nicholas J. White, Francois Nosten, Joel Tarning   +14 more
wiley   +1 more source

Rapid Identification of Drug-Resistant Strains of Mycobacterium leprae through qPCR High-Resolution Melt Analysis (HRMA): A High-Throughput and Effective Screening Method

Indian Dermatology Online Journal
Background: Rapid detection of drug-resistant Mycobacterium leprae is essential for effective treatment. Real-time polymerase chain reaction high-resolution melt (qPCR–HRM) analysis is a promising tool for this purpose.
Rahul Sharma, Itu Singh, Saurabh Gupta
doaj   +1 more source

Brucella abortus RB51 Persistent Infection and Milk Shedding in Vaccinated Dairy Cattle: A Public Health Risk

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Brucellosis, caused by a group of bacteria within the genus Brucella, is a zoonotic disease of significant public health concern. The RB51 strain vaccine is used to combat cattle brucellosis but has potential health consequences for exposed humans.
Elizabeth S. Hines, Sara F. Margrey, Stephanie W. Cox, Christine Quance, Tyler C. Thacker, Patricia L. Collins, Susan Rollo, Leslie L. Bulaga‐Seraphin, Aimee Hunt, Gary Stevens, Kyran Cadmus, Maria Negron, Grishma Kharod, Rebekah Tiller, Suelee Robbe‐Austerman, Jason E. Lombard   +15 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Rifampicin and isoniazid resistance not promote fluoroquinolone resistance in Mycobacterium smegmatis

PLOS ONE
Background The emergence of drug-resistant Tuberculosis (TB) has made treatment challenging. Although fluoroquinolones (FQs) are used as key drugs in the treatment of multidrug-resistant tuberculosis (MDR-TB), the problem of FQs resistance is becoming increasingly serious. Rifampicin (RIF) resistance is considered a risk factor for FQs resistance. The
Qin Zhou, Na Pu, Ge Xu, Hangchi Liu, Xudong Jia, Xiaomin Wang, Peng Xu   +6 more
openaire   +4 more sources

Artificial Intelligence Resources for the Screening of Titles and Abstracts in Systematic Reviews: A Scoping Review

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 5, September 2026.
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán, Sara Elena Ortiz Bonett, Eliana‐Isabel Rodríguez‐Grande, Alvaro David Orjuela‐Cañón, Oscar J. Perdomo, Guillermo Sánchez‐Vanegas   +5 more
wiley   +1 more source

A Risk‐Based Framework for Ranking Microbiological Hazards and Identifying Mitigation Strategies for Dried Fruits, Vegetables, Herbs, and Spices Used in Ready‐to‐Eat Foods

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Low water activity ingredients, including dried fruits, vegetables, herbs, and spices, are widely used in ready‐to‐eat (RTE) and non‐RTE foods. Although low water activity limits microbial growth, bacterial pathogens can survive for extended periods in these products.
Heidy M. W. den Besten, Linda J. Harris, Jennifer C. Acuff, Francois Bourdichon, Rob Limburn, Andreja Rajkovic, Anett Winkler, Polly D. Courtney   +7 more
wiley   +1 more source

Therapeutic choices in rifampicin-resistant tuberculosis [PDF]

The Lancet Infectious Diseases, 2016
Shashank, Ganatra, Zarir, Udwadia, Camilla, Rodrigues   +2 more
openaire   +2 more sources

A tomato MIK2‐clade receptor is involved in the perception of a Fusarium‐derived elicitor

New Phytologist, Volume 251, Issue 5, Page 2777-2798, September 2026.
Fusarium elicitor responsivness and MIK2‐clade proteins are conserved across plant families. Summary Plants continuously monitor their environment to adapt to threats affecting health and fitness. Cell‐surface receptors detect conserved microbe‐associated molecular patterns (MAMPs) or endogenous immunogenic signals to activate signaling pathways that ...
Julian Maroschek, Yvonne Rösgen, Clemens Rössner, Simon Snoeck, Claus Schwechheimer, Cyril Zipfel, Ralph Hückelhoven   +6 more
wiley   +1 more source