Results 81 to 90 of about 2,415,366 (239)

Evaluating the performance of the InnowaveDx MTB/RIF/INH for simultaneous detection of Mycobacterium tuberculosis and resistance to rifampicin and isoniazid

Journal of Global Antimicrobial Resistance
Objective: To evaluate the diagnostic performance of the InnowaveDx MTB/RIF/INH assay for the simultaneous detection of Mycobacterium tuberculosis and resistance to rifampicin and isoniazid. Methods: We evaluated the performance of the InnowaveDx MTB/RIF/
Dapeng Fan, Hao Li, Xuechai Shang, Miaofen Yang, Huanyu Li, Yongning Yue, Long Cai   +6 more
doaj   +1 more source

SNPs leading to rifampicin, isoniazid and pyrazinamide resistance in XDR strains.

, 2015
All strain were resistant to rifampicin (RIF, 1 μg/ml), isoniazid (INH, 1 μg/ml) and pyrazinamide (PZA, 100μg/ml). ‘#’ mutations in the rifampicin- resistance determining region (RRDR), the number in parenthesis indicates the number of MTB isolates from ...
Mridul Nair (590036), Asho Ali (73920), Kim Mallard (362508), Taane G. Clark (106263), Rumina Hasan (73926), Zahra Hasan (73921), Ruth McNerney (227467), Francesc Coll (495630), Arnab Pain (37809), Grant Hill-Cawthorne (696209)   +9 more
core   +1 more source

Comparative Diagnostic Performance of Three Commercial Real‐Time PCR Assays for the Detection of Mycobacterium tuberculosis Complex in Bronchial Washing Specimens: A Large Retrospective Study

Journal of Clinical Laboratory Analysis, EarlyView.
This large retrospective study compared the diagnostic performance of three commercial real‐time PCR assays (AdvanSure TB/NTM, Cobas MTB, and Xpert MTB/RIF) for MTBC detection in 3348 bronchial washing specimens. In a head‐to‐head comparison of 740 specimens, the Cobas MTB and Xpert MTB/RIF assays showed markedly higher sensitivity than the AdvanSure ...
Jimyung Kim, Yumi Park
wiley   +1 more source

THE MOLECULAR GENETIC FEATURES OF RIFAMPICIN RESISTANCE AND THE PREVALENCE OF rpoB GENE MUTATIONS IN THE SARATOV REGION

Туберкулез и болезни лёгких, 2014
The prevalence and spectrum of mutations in the rpoB gene encoding for rifampicin resistance were studied in 257 active pulmonary tuberculosis patients living in the Saratov Region. Investigations were performed using a TB-Biochip MDR kit (Russia).
T. Yu. Salina, T. I. Morozova
doaj   +1 more source

Comparative results of LPA with GeneXpert for rifampicin resistance.

, 2014
Comparative results of LPA with GeneXpert for rifampicin resistance.
Rashed Noor (578403), Farjana Rahman (578402), Saurab Kishore Munshi (578399), Md. Mostafizur Rahman (194740), S. M. Mostofa Kamal (578400), Tafsina Haque Aurin (578398), Thaythayhla Marma (578401), Md. Shamim Hossain (500572)   +7 more
core   +1 more source

Dosing HIV integrase inhibitors with enzyme inducers: Convenience vs. control?

British Journal of Clinical Pharmacology, EarlyView.
Catia Marzolini, Saye Khoo
wiley   +1 more source

Integrating anaerobic and photochemical processes: UV–vis‐driven post‐treatment for micropollutant abatement and toxicity control in UASB secondary effluent

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Upflow anaerobic sludge blanket (UASB) reactors are widely used in low‐ and middle‐income countries, but secondary effluents may still contain organic micropollutants and residual toxicity. This study evaluated UV–Vis photolysis and UV/H2O2 as post‐treatment options for UASB secondary effluent (SE), integrating micropollutant ...
Fernando Rodrigues‐Silva, Gabriella P Masceno, Paloma P Panicio, Magno Lange Albuquerque, Rafaela Imoski, Wanessa A Ramsdorf, Liziê DT Prola, Maria Clara VM Starling, Camila C Amorim, Fernando H Passig, Marcus V Liz   +10 more
wiley   +1 more source

Subinhibitory Concentrations of Rifampicin Synergize with Linezolid to Delay Resistance Evolution in Clinical Methicillin-Resistant Staphylococcus Aureus

Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant pathogen. Long-term clinical use of linezolid readily induces bacterial resistance in MRSA.
Yalong Qi, Ziyan Chen, Menglin Hu, Sailan Wang, Chuanwei Zhang, Chunhua Peng, Lu Lai, Fangrui Liang, Xiaohui Huang   +8 more
core   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Molecular characterisation of rifampicin-resistant Mycobacterium tuberculosis strains from Malawi

African Journal of Laboratory Medicine, 2017
Background: Availability and access to the detection of resistance to anti-tuberculosis drug sremains a significant challenge in Malawi due to limited diagnostic services.
Tarsizio Chikaonda, Irene Ketseoglou, Nelson Nguluwe, Robert Krysiak, Isaac Thengolose, Felix Nyakwawa, Nora E. Rosenberg, Christopher Stanley, James Mpunga, Irving F. Hoffman, Maria A. Papathanasopoulos, Mina Hosseinipour, Lesley Scott, Wendy Stevens   +13 more
doaj   +1 more source