Results 61 to 70 of about 46,701 (237)

Antimicrobial Envelopes for Cardiac Device Infection Prevention: A Meta‐Analysis of Randomized and Matched Studies

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Cardiac implantable electronic device (CIED)‐associated infections are a significant procedural complication. Antibacterial envelopes have emerged as a potential strategy to mitigate this risk, though the evidence regarding their prognostic benefit remains inconclusive.
Alonzo Armani Prata, Luís Fernando Ferreira Cavalcante, Gabriela Blanco Stutz, Thalia Melamed, Caio Rezende Lima, Andrew H. Locke, Alexandra Régia Dantas Brígido   +6 more
wiley   +1 more source

De Novo Design and Synthesis of Novel Benzoxazinone Derivatives Targeting Dihydroxyacid Dehydratase

Plant Biotechnology Journal, EarlyView.
ABSTRACT Dihydroxyacid dehydratase (DHAD), a key enzyme in the branched‐chain amino acid (BCAA) synthesis pathway, is a promising herbicide target. Currently, no commercial herbicides target DHAD, and no inhibitors are in development. Structural analysis suggests that coordination with iron–sulfur clusters and hydrophobic interactions with Tyr215 and ...
Bo He, Yanhao Hu, Xu He, Wang Chen, Wei Yan, Xin Zang, Jiahai Zhou, Yonghao Ye   +7 more
wiley   +1 more source

Comparison of Rifampin and Isoniazid for Latent Tuberculosis Infection in Kidney Transplant Candidates: Focus on Tolerability and Treatment Completion

Transplant Infectious Disease, EarlyView.
This study comparing 4‐month rifampin with 9‐month isoniazid for latent tuberculosis in kidney transplant candidates showed higher treatment completion rates and no transaminase elevations in the rifampin group. However, some patients experienced an increase in blood pressure while taking antihypertensive medications known to interact with rifampin ...
Jacques Simkins, Julia Bini Viotti, Yoichiro Natori, Shweta Anjan, Adela Mattiazzi, Mariella Ortigosa‐Goggins, Giselle Guerra, David Roth, Warren Kupin, Javier A. Pagan, Franco Cabeza, Gaetano Ciancio, Mahmoud Morsi, Michele I. Morris   +13 more
wiley   +1 more source

The Study of the Protective Effect of Black Cumin (Nigella sativa linn.)Ethanolic Extract Against Rifampin-induced Hepatotoxicity in Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives:Anti-tuberculosis drug, rifampin, is toxic for liver. This study was conducted to determine the preventive effects of black cumin (Nigella sativaLinn.) extract against rifampin-induced hepatotoxicity in rats. Methods: In this
Mehrdad Neshat Gharamaleki, Daryoush Mohajeri   +1 more
doaj  

New combination for patients with latent tuberculosis infection: A pilot study

Journal of Medical Sciences, 2018
Background: Latent tuberculosis infection (LTBI) is characterized by the presence of immune responses to Mycobacterium tuberculosis without clinical evidence of active TB.
Te-Yu Lin, Feng-Cheng Liu
doaj   +1 more source

Evidence‐Based and Consensus‐Based Approach to the Treatment of Hidradenitis Suppurativa: Based on the Updated European SK2 Guidelines for the Treatment of Hidradenitis Suppurativa/Acne Inversa

JEADV Clinical Practice, EarlyView.
Wayne P. Gulliver
wiley   +1 more source

Mycobacterium avium Infection in a Domestic Shorthair Cat Following Subdermal Hyaluronic Acid Filler Injection

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To describe the diagnosis and treatment of a Mycobacterium avium (M. avium) infection in a cat following subdermal hyaluronic acid (HA) filler injection. Animal Studied A five‐year‐old spayed female domestic shorthair cat with chronic inferior lateral entropion and chronic feline atopic skin syndrome (FASS).
Alexandra E. Bergen, Callie Miller, J. Seth Eaton, Lara M. Tomich, Jennifer L. Heyward, Taylor A. Opgenorth   +5 more
wiley   +1 more source

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 329-347, February 2026.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Enhanced Biofilm Disruption in Methicillin-Resistant Staphylococcus aureus Using Rifampin and Fluoroquinolone Combinations

Pathogens
Staphylococcus aureus biofilms complicate the treatment of device-related infections. We hypothesized that combining rifampin with fluoroquinolones could eradicate biofilms even in antimicrobial-resistant S. aureus strains.
Yu Ri Kang, Joo-Young Park, Doo Ryeon Chung, Minhee Kang, Jae-Hoon Ko, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Kyong Ran Peck   +8 more
doaj   +1 more source

Synergism of Linezolid and Rifampin to Combat Multidrug-Resistant Environmental Enterococci Isolates

پیاورد سلامت, 2022
Background and Aim: Wastewater is one of the most dangerous and important sources of pathogens and their treatment does not always guarantee the elimination of pathogenic bacteria.
Mobina Noori, Leila Fozouni, Ania Ahani Azari   +2 more
doaj