Defining the minimum inhibitory concentration of 22 rifamycins in iron limited, physiologic medium against Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae clinical isolates. [PDF]
PLoS ONE, 2023 Recently, we reported rifabutin hyper-activity against Acinetobacter baumannii. We sought to characterize if any additional rifamycins (n = 22) would also display hyper-activity when tested in iron-limited media against A. baumannii, K. pneumoniae, and E.
Peggy Lu +8 more
doaj +2 more sources
Biosynthesis of Rifamycins (Ansamycins) and Microbial Production of Shikimate Pathway Precursors, Intermediates, and Metabolites [PDF]
CHIMIA, 1985 Is the elucidation of biosynthetic pathways of academic interest only, or are there enough valuable spin-offs to make biogenetic studies attractive for a research laboratory in a pharmaceutical company?
Oreste Ghisalba
doaj +3 more sources
Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer. [PDF]
PLoS Neglected Tropical Diseases, 2018 TRIAL REGISTRATION:ClinicalTrials.gov NCT03474198, NCT01659437.
Paul J Converse +10 more
doaj +3 more sources
Hospital-Associated Antimicrobial Resistant Bacteria on 95 Mobile Phones: An International Metagenomic "Phonome" Analysis. [PDF]
MicrobiologyopenOn average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Goldsworthy A +12 more
europepmc +2 more sources
, 2022 Archive of rifamycins containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875) +5 more
core +1 more source
Looking Back to Amycolatopsis: History of the Antibiotic Discovery and Future Prospects
Antibiotics, 2021 The emergence of antibiotic-resistant pathogenic bacteria in recent decades leads us to an urgent need for the development of new antibacterial agents. The species of the genus Amycolatopsis are known as producers of secondary metabolites that are used ...
Olga V. Kisil +2 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2022 : Objectives: We conducted an in vitro investigation of the activity of rifamycins against planktonic and biofilm states of Staphylococcus aureus and Staphylococcus epidermidis isolates from patients with prosthetic joint infections (PJIs ...
Yunjung Lee +9 more
doaj +1 more source
Antibiofilm and intraosteoblastic activities of rifamycins against Staphylococcus aureus: promising in vitro profile of rifabutin [PDF]
, 2020 BACKGROUND: Targeting biofilm-embedded and intraosteoblastic Staphylococcus aureus, rifampicin gained a pivotal role in bone and joint infection (BJI) treatment. Two other rifamycins, rifabutin and rifapentine, may represent better-tolerated alternatives,
Josse, Jérôme +7 more
core +1 more source
Gut microbiome amplicon sequence variants (ASVs) and sample data from patients with tuberculosis infection before, during, and after treatment with rifamycins [PDF]
, 2022 The phyloseq object contains amplicon sequence variants (ASV) and associated sample data collected from six patients infected with tuberculosis (LTBI) and six healthy controls.
Marie Nancy Séraphin (11427454)
core +1 more source
Scientific Reports, 2023 Tuberculosis (TB) preventive therapy (TPT) is an effective strategy to eliminate TB in low-incidence settings. Shorter TPT regimens incorporating the antimicrobial class of rifamycins are designed to improve adherence and completion rates but carry the ...
Marie Nancy Séraphin +6 more
doaj +1 more source