Results 21 to 30 of about 6,382 (203)
Pathogens, 2023 Infective endocarditis (IE) is a rare but increasingly prevalent disease with high morbidity and mortality, requiring antimicrobials and at times surgical intervention. Through the decades of healthcare professionals’ experience with managing IE, certain
Jennifer L. Adema +5 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Antibacterial activity of rifamycins for M. smegmatis with comparison of oxidation and binding to tear lipocalin [PDF]
, 2014 A mutant of Mycobacterium smegmatis is a potential class I model substitute for Mycobacterium tuberculosis. Because not all of the rifamycins have been tested in this organism, we determined bactericidal profiles for the 6 major rifamycin derivatives ...
Glasgow, Ben J +2 more
core +1 more source
IDCases, 2023 Background: Mycobacterium xenopi is one of the most common pathogens responsible for non-tuberculosis mycobacteria (NTM) pulmonary diseases, which are associated with poor prognosis in immunocompromised patients.
Antoine Hamon +4 more
doaj +1 more source
In vitro activity of rifamycins alone and in combination with other antibiotics against Chlamydia trachomatis [PDF]
, 1983 Rifamycins are highly active against Chlamydia trachomatis, but the possible develop-ment of resistance has been of concern. The ability of rifampin, rifamide, and DL473 to induce resistance in chlamydiae and the effect of combinations of antibiotics on ...
Geoffrey L. Ridgway +4 more
core +1 more source
Comprehensive Study on Structure−Activity Relationships of Rifamycins: Discussion of Molecular and Crystal Structure and Spectroscopic and Thermochemical Properties of Rifamycin O [PDF]
, 2016 The mechanism of action of rifamycins against bacterial DNA-dependent RNA polymerase has been explained on the basis of the spatial arrangement of four oxygens which can form hydrogen bonds with the enzyme.
Alessia Bacchi (639107) +3 more
core +1 more source
Trials, 2020 Background Tuberculosis (TB) is a significant public health problem that causes substantial morbidity and mortality. Current first-line anti-TB chemotherapy, although very effective, has limitations including long-treatment duration with a possibility of
Ruth Nabisere +8 more
doaj +1 more source
Abnormal Dexamethasone Suppression Tests in a Rifapentine-Treated Patient With Primary Aldosteronism
Frontiers in Endocrinology, 2020 Aldosterone-producing adenoma (APA) is a main cause of primary aldosteronism (PA). Given that a large benign-appearing unilateral masse (>1 cm in diameter) may represent an aldosterone and cortisol-co-secreting adenoma, dexamethasone suppression ...
Hongman Wang +7 more
doaj +1 more source
PLoS ONE, 2013 BackgroundDevelopment of resistance to antituberculosis drugs during treatment (i.e., acquired resistance) can lead to emergence of resistant strains and consequent poor clinical outcomes. However, it is unknown whether Mycobacterium tuberculosis complex
Courtney M Yuen +4 more
doaj +1 more source
BMC Research Notes, 2023 Objective We present 16s rRNA gene sequencing (V1-V2 region) and sample data from a pilot observational cohort study to describe the gut microbiota dynamics of subjects with latent tuberculosis infection (LTBI) treated with daily 600 mg rifampicin for ...
Marie Nancy Séraphin +3 more
doaj +1 more source