Results 51 to 60 of about 4,732 (172)
The psychiatric side-effects of rimonabant [PDF]
Revista Brasileira de Psiquiatria, 2009 OBJECTIVE: Experimental evidence has suggested that drugs that enhance cannabinoid type-1 (CB1) receptor activity may induce anxiolytic and antidepressant effects, whilst the opposite has been reported with antagonists. Thus, the objective of the present review is to discuss the potential psychiatric side-effects of CB1 receptor antagonists, such as ...
Fabrício A, Moreira +1 more
openaire +2 more sources
European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source
Pharmaceuticals, 2010 Available anti-obesity pharmacotherapy options remain very limited and development of more effective drugs has become a priority. The potential strategies to achieve weight loss are to reduce energy intake by stimulating anorexigenic signals or by ...
Fernando Cordido, Mª Luisa Isidro
doaj +1 more source
Advances in the Different Synthetic Routes of Fluorinated Hydrazines
The Chemical Record, Volume 26, Issue 6, June 2026.This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley +1 more source
Anti-obesity activity of Erythrina subumbrans (Hassk.) Merr leaves extract in high fructose-induced obesity in Wistar rats [PDF]
Journal of HerbMed PharmacologyIntroduction: Obesity is known to lead to the development of metabolic disorders and Erythrina subumbrans (Hassk.) Merr has shown the potential in alleviating some diseases. This study aimed to assess the anti-obesity activity of the ethanol extract of E.
Elis Susilawati +5 more
doaj +1 more source
Artery Research, 2020 Objectives: Cannabinoid receptors CB1R and CB2R are expressed in the vascular smooth muscle cells (VSMCs) and may contribute to vascular remodeling process (O’Sullivan, 2015).
Bettina Greiner +4 more
doaj +1 more source
Brain and Behavior, Volume 16, Issue 5, May 2026.This study explored the association between the FAAH rs324420 polymorphism and substance use disorders in individuals with methamphetamine, opioid, and combined use. The rs324420 CA genotype was linked to a reduced risk of substance use disorder, while higher craving scores were observed in individuals with combined opioid–methamphetamine use. ABSTRACT
Özlem Erekli‐Arat +4 more
wiley +1 more source
European Journal of Pain, Volume 30, Issue 5, May 2026.ABSTRACT Background Many people use cannabis to self‐medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta‐9‐tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our previous research with the opioid morphine suggests persistent pain will increase the magnitude and duration of
Michael M. Morgan, Christa M. Hickey
wiley +1 more source
Phytotherapy Research, Volume 40, Issue 5, Page 2604-2631, May 2026.Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli +4 more
wiley +1 more source
Health Technology Assessment, 2012 Background: Obesity [defined as a body mass index (BMI) ≥ 30 kg/m2] represents a considerable public health problem and is associated with a significant range of comorbidities and an increased mortality risk.
R Ara +14 more
doaj +1 more source