Results 71 to 80 of about 6,428 (208)
Effectiveness of Alcohol Use Disorder Pharmacotherapies by Sex: Systematic Review and Meta‐Analysis
Drug and Alcohol Review, Volume 45, Issue 5, July 2026.ABSTRACT Issues Alcohol use disorder (AUD) shows sex‐related differences in prevalence, harm and treatment response. Despite growing interest in sex differences, evidence synthesis evaluating pharmacotherapy effectiveness by sex remains limited. Approach Web of Science, PubMed, Scopus, PsycINFO and Cochrane were searched twice.
Juliette Allen +11 more
wiley +1 more source
Health Technology Assessment, 2012 Background: Obesity [defined as a body mass index (BMI) ≥ 30 kg/m2] represents a considerable public health problem and is associated with a significant range of comorbidities and an increased mortality risk.
R Ara +14 more
doaj +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source
Role of the endogenous cannabinoid system in nicotine addiction: novel insights
Frontiers in Psychiatry, 2015 Several lines of evidence have shown that the endogenous cannabinoids are implicated in several neuropsychiatric diseases. Notably, preclinical and human clinical studies have shown a pivotal role of the cannabinoid system in nicotine addiction.
Islam Hany Gamaleddin +8 more
doaj +1 more source
Advances in the Different Synthetic Routes of Fluorinated Hydrazines
The Chemical Record, Volume 26, Issue 6, June 2026.This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley +1 more source
, 2011 Aim: To investigate whether rimonabant, a cannabinoid receptor antagonist , had inhibitory effects on inflammatory reactions in human umbilical vein endothelial cells (HUVEC).
黃南嵐;莊志明;王怡和;薛嘉祥;梁耀仁;林俊立;蔡佳醍;賴凌平 +1 more
core
Vanilloid VR1 receptor is involved in rimonabant-induced neuroprotection
, 2006 1 Recently, a potential neuroprotective effect of rimonabant, independent of the CB1 receptor interaction, has been proposed. In the present study, the role of transient receptor potential channel vanilloid subfamily member 1, named VR1, on ...
A. Zani +4 more
core +1 more source
Brain and Behavior, Volume 16, Issue 5, May 2026.This study explored the association between the FAAH rs324420 polymorphism and substance use disorders in individuals with methamphetamine, opioid, and combined use. The rs324420 CA genotype was linked to a reduced risk of substance use disorder, while higher craving scores were observed in individuals with combined opioid–methamphetamine use. ABSTRACT
Özlem Erekli‐Arat +4 more
wiley +1 more source
, 2011 Aim: To investigate whether rimonabant, a cannabinoid receptor antagonist , had inhibitory effects on inflammatory reactions in human umbilical vein endothelial cells (HUVEC).
黃南嵐;莊志明;林俊立;蔡佳醍;賴凌平 +1 more
core
Effect of rimonabant on oesophageal motor function in man
, 2011 BACKGROUND: Cannabinoid type 1 (CB1) receptors are implicated in the control of transient lower oesophageal sphincter relaxations (TLESRs) in animals. In man, it is unclear whether CB1 receptors are involved in the control of oesophageal function.
A. Gasbarrini +19 more
core +1 more source