Photochemical Electrocyclic Ring Closure and Leaving Group Expulsion from N-(9-oxothioxanthenyl)Benzothiophene Carboxamides [PDF]
, 2013 N-(9-Oxothioxanthenyl)benzothiophene carboxamides bearing leaving groups (LG− = Cl−, PhS−, HS−, PhCH2S−) at the C-3 position of the benzothiophene ring system photochemically cyclize with nearly quantitative release of the leaving group, LG−.
Sarker, Majher I. +3 more
core +3 more sources
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Bioorganic and Bioinorganic Chemistry
CHIMIA, 2010 The interdisciplinary projects in bioinorganic and bioorganic chemistry of the Department of Chemistry, University of Basel led to the preparation of new systems that mimic biologically important processes and to the discovery of compounds from ...
Edwin C. Constable +7 more
doaj +1 more source
, 2017 Ring polymers are prevalent in natural and engineered systems, including circular bacterial DNA, crown ethers for cation chelation, and mechanical nanoswitches.
Ferguson, Andrew, Wang, Jiang
core +1 more source
Molecular gas chemistry in AGN. II. High-resolution imaging of SiO emission in NGC1068: shocks or XDR? [PDF]
, 2010 This paper is part of a multi-species survey of line emission from the molecular gas in the circum-nuclear disk (CND) of the Seyfert 2 galaxy NGC1068. Single-dish observations have provided evidence that the abundance of silicon monoxide(SiO) in the CND ...
A. Fuente +87 more
core +3 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Synthesis of Ti(OH)OF ⋅ 0.66 H2O in Imidazolium‐based Ionic Liquids
ChemistryOpen, 2021 The influence of the cation of imidazolium‐derived ionic liquids (ILs) on a low‐temperature solution‐based synthesis of hexagonal tungsten bronze (HTB) type Ti(OH)OF ⋅ 0.66 H2O and bronze‐type TiO2(B) is investigated.
Melanie Sieland +3 more
doaj +1 more source
Impact of the Recovery on Concentrating Acetic Acid with Low-Pressure Reverse-Osmosis Membranes
Membranes, 2021 This work deals with the optimization of the concentration of volatile fatty acids (VFAs) using low-pressure reverse osmosis (LPRO) membranes. Membrane filtration of a synthetic solution simulating the product of biomass hydrolysis was performed ...
Giorgio Pratofiorito +2 more
doaj +1 more source
Intramolecular pi-pi stacking interactions in 2-substituted N,N-dibenzylaziridinium ions and their regioselectivity in nucleophilic ring-opening reactions [PDF]
, 2009 The ring opening of 2-substituted N,N-dibenzylaziridinium ions by bromide is known to occur exclusively at the Substituted aziridine carbon atom via ail S(N)2 mechanism, whereas the opposite regioselectivity has been observed as the main pathway for ring
Catak, Saron +4 more
core +2 more sources
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source