Results 71 to 80 of about 108,684 (302)
Salen–scandium(III) complex-catalyzed asymmetric (3 + 2) annulation of aziridines and aldehydes
Beilstein Journal of Organic ChemistryOxazolidine is one of the crucial structural moieties of biologically active compounds. A salen–scandium triflate complex-catalyzed asymmetric (3 + 2) annulation of dialkyl 1-sulfonylaziridine-2,2-dicarboxylates and aldehydes generated optically active ...
Linqiang Wang, Jiaxi Xu
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
, 2009 The International Tree-Ring Data Bank (ITRDB) is an invaluable resource, providing access to a massive and growing cache of tree-ring data. Oxygen, carbon, nitrogen and hydrogen isotope treering studies, which have provided valuable climatic and ...
Csank, Adam Z.
core
Ring Expansion via Olefin Metathesis
, 2016 Various macrocycles were prepared in one step by a novel ring-expansion method using olefin ...
Tae-Lim Choi (1500892) +2 more
core +1 more source
Журнал органічної та фармацевтичної хіміїThe literature review discusses and systematizes synthetic approaches to medium-sized cycles and macrocycles based on ring expansion reactions of bi- or polycyclic systems via C-N bond cleavage. Ring expansion reactions of bicyclic ammonium salts proceed
Viacheslav Lysenko +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ru(Ⅱ)—catalyzed ring expansion of alkynylcyclopropanes in the presence of sulfonamides
, 2013 Ru(Ⅱ)—catalyzed ring expansion of alkynylcyclopropanes in the presence of ...
陈雨叶 +3 more
core
Divergent Cascade Ring Expansion Reactions of Acryloyl Imides [PDF]
Macrocyclic and medium-sized ring ketones, lactones and lactams can all be made from common acryloyl imide starting materials via divergent, one-pot cascade ring expansion reactions.
Pogranyi, Balazs +9 more
core +1 more source