Results 171 to 180 of about 15,574 (187)

RIPK1 Is Not Essential for TNFR1-Induced Activation of NF-κB

Cell Death and Differentiation, 2010
On TNF binding, receptor-interacting protein kinase 1 (RIPK1) is recruited to the cytoplasmic domain of TNFR1, at which it becomes ubiquitylated and serves as a platform for recruitment and activation of NEMO/IKK1/IKK2 and TAK1/TAB2.
Ueli Nachbur, Ian E. Gentle, John Silke
exaly   +2 more sources

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Receptor-Interacting Protein Kinase 1 (RIPK1) as a Therapeutic Target

Nature Reviews Drug Discovery, 2020
Lauren Mifflin, Junying Yuan
exaly  

RIPK1 Kinase-Dependent Death: A Symphony of Phosphorylation Events

Trends in Cell Biology, 2020
Mathieu Jm Bertrand, Yves Dondelinger, Tom Delanghe   +2 more
exaly  

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway

Molecular Cell, 2021
Huibing Wang, Ayaz Najafov, Alban Ordureau   +2 more
exaly  

TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation During Development and in Aging

Cell, 2018
Palak Amin, Joshua Levin, Hong Zhu
exaly  

The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex

Cell, 2018
Hao Wu, Miguel Mompeán, Güneş Bozkurt
exaly  

RIPK1 Protects Epithelial Cells

Nature Reviews Molecular Cell Biology, 2014
Kim Baumann
exaly  

Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling

Trends in Cell Biology, 2016
Nieves Peltzer, Henning Walczak, Maurice Darding   +2 more
exaly  

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

Molecular Cell, 2018
Peter Vandenabeele, Jianbin Ruan, Hao Wu
exaly  

Targeting RIPK1 for the Treatment of Human Diseases

Proceedings of the National Academy of Sciences of the United States of America, 2019
Alexei Degterev, Junying Yuan
exaly