Results 41 to 50 of about 423,061 (280)
Rotavirus infection induces transient pancreatic involution and hyperglycemia in weanling mice. [PDF]
PLoS ONE, 2014 Rotavirus is a ubiquitous double-stranded RNA virus responsible for most cases of infantile gastroenteritis. It infects pancreatic islets in vitro and is implicated as a trigger of autoimmune destruction of islet beta cells leading to type 1 diabetes ...
Margo C Honeyman +5 more
doaj +1 more source
A phagocytic route for uptake of double-stranded RNA in RNAi. [PDF]
PLoS ONE, 2011 RNA interference (RNAi) has a range of physiological functions including as a defence mechanism against viruses. To protect uninfected cells in a multicellular organism, not only a cell-autonomous RNAi response is required but also a systemic one ...
João J E Rocha +3 more
doaj +1 more source
Heliyon, 2021 Background: Emerging viruses could be detected before reaching pandemic level if universal viral detection screening was routinely used. Double-stranded RNA (dsRNA) is the only common antigen across most viral families.
Kornthara Kawang +5 more
doaj +1 more source
A model for the force stretching double-stranded chain molecules
, 2002 We modify and extend the recently developed statistical mechanical model for predicting the thermodynamic properties of chain molecules having noncovalent double-stranded conformations, as in RNA or ssDNA, and $\beta-$sheets in protein, by including the ...
Fei Liu +5 more
core +1 more source
Evidence that avian reovirus σNS is an RNA chaperone: implications for genome segment assortment. [PDF]
, 2015 Reoviruses are important human, animal and plant pathogens having 10-12 segments of double-stranded genomic RNA. The mechanisms controlling the assortment and packaging of genomic segments in these viruses, remain poorly understood.
Ault, J +3 more
core +1 more source
Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients. [PDF]
PLoS ONE, 2014 Potent RNase activities were found in the serum of mammals but the physiological function of the RNases was never well illustrated, largely due to the caveats in methods of RNase activity measurement.
Weiyan Huang +6 more
doaj +1 more source
Two Classes of Silencing RNAs Move between Caenorhabditis elegans Tissues [PDF]
, 2013 Organism-wide RNA interference (RNAi) is due to the transport of mobile silencing RNA throughout the organism, but the identities of these mobile RNA species in animals are unknown. Here, we present genetic evidence that both the initial double-stranded
Garcia, Giancarlo +2 more
core +1 more source
Why double-stranded RNA resists condensation [PDF]
Nucleic Acids Research, 2014 The addition of small amounts of multivalent cations to solutions containing double-stranded DNA leads to inter-DNA attraction and eventual condensation. Surprisingly, the condensation is suppressed in double-stranded RNA, which carries the same negative charge as DNA, but assumes a different double helical form.
Tolokh, Igor S. +7 more
openaire +3 more sources
Reverse Genetics for Double-Stranded RNA Viruses
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2009 Resumen en inglès, ver archivo ...
H. Attoui +3 more
doaj +1 more source
High-Pressure-Sprayed Double Stranded RNA Does Not Induce RNA Interference of a Reporter Gene
Frontiers in Plant Science, 2020 In plants, RNA interference (RNAi) is an effective defense mechanism against pathogens and pests. RNAi mainly involves the micro RNA and the small interfering RNA (siRNA) pathways.
Veli Vural Uslu +4 more
doaj +1 more source