<i>VILMIR</i> is a <i>trans</i>-acting long noncoding RNA that enhances the host interferon response in human epithelial cells. [PDF]
John K +7 more
europepmc +1 more source
Abstract Background Activation of complement protein C3 generally enhances antibody responses and C3‐null mice have decreased antibody‐based immunity. Mener et al. have reported a paradoxical suppressor function for C3 in alloimmunization to transfused RBCs as alloantibodies are increased in C3‐null mice.
Arijita Jash +2 more
wiley +1 more source
The Roles of Plant MicroRNAs in Defence Against Pathogens. [PDF]
Mahamadou AM +6 more
europepmc +1 more source
ABSTRACT Background microRNAs (miRNA) have been proposed as biomarkers for pancreatitis in dogs due to their high peak concentrations and experimental correlation with acinar cell injury. However, analytical validation and the effect of interfering substances are unknown.
Caylen Erger +2 more
wiley +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
Systematic identification and characterization of virus lncRNAs suggests extensive structural mimicry of host lncRNAs. [PDF]
Fu P +6 more
europepmc +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
RETRACTION: Pathogenesis of Psoriasis via MiR-149-5p/AKT1 Axis by Long Noncoding RNA BLACAT1. [PDF]
europepmc +1 more source
A novel disulfidptosis-related lncRNA signature for development and evaluation of hepatocellular carcinoma prognosis. [PDF]
Bian G, Zhu P, Wang Q.
europepmc +1 more source

