Results 51 to 60 of about 498,663 (149)

Novel models for RNA splicing that involve a small nuclear RNA.

open access: yesProceedings of the National Academy of Sciences, 1981
Nucleotide sequences of mammalian small nuclear RNAs (snRNAs) have been analyzed with a computer program for complementarity with sequences around a splice junction of various eukaryotic mRNA precursors (pre-mRNAs). A region in U2 RNA or some other snRNAs can form base pairs with both exons surrounding an intron of certain pre-mRNAs and, thereby, can ...
Yasumi Ohshima   +3 more
openaire   +4 more sources

Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis

open access: yesBiology Open, 2014
Spliceosomal small nuclear ribonucleoproteins (snRNPs) are enriched in the Cajal body (CB). Guide RNAs, known as small Cajal body-specific RNAs (scaRNAs), direct modification of the small nuclear RNA (snRNA) component of the snRNP.
Isioma I. Enwerem   +5 more
doaj   +1 more source

A small RNA ofMycoplasma capricolumthat resembles eukaryotic U6 small nuclear RNA

open access: yesNucleic Acids Research, 1993
Mycoplasma capricolum, a parasitic prokaryote, contains several small stable RNAs, besides rRNAs and tRNAs. One of them, designated MCS4 RNA (125 nucleotides in length), has been isolated and sequenced. This RNA is abundant in the cell, and is encoded by two genes.
Chisato Ushida, Akira Muto
openaire   +4 more sources

Mpn1, Mutated in Poikiloderma with Neutropenia Protein 1, Is a Conserved 3′-to-5′ RNA Exonuclease Processing U6 Small Nuclear RNA

open access: yesCell Reports, 2012
Clericuzio-type poikiloderma with neutropenia (PN) is a rare genodermatosis associated with mutations in the C16orf57 gene, which codes for the uncharacterized protein hMpn1.
Vadim Shchepachev   +4 more
doaj   +1 more source

HRDE-2 drives small RNA specificity for the nuclear Argonaute protein HRDE-1

open access: yesNature Communications
RNA interference (RNAi) is a conserved gene silencing process that exists in diverse organisms to protect genome integrity and regulate gene expression. In C.
Shihui Chen, Carolyn M. Phillips
doaj   +1 more source

RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers

open access: yesTumor Biology, 2017
RNA editing is a widespread post-transcriptional mechanism that confers specific and reproducible nucleotide changes in selected RNA transcripts and plays a critical role in many human cancers.
Xueda Hu   +11 more
doaj   +1 more source

Molecular Mechanisms and Clinical Implications of Noncoding RNAs in Cancer

open access: yesNon-Coding RNA
Noncoding RNAs (ncRNAs), which include small nuclear RNAs (snRNAs), small nucleolar RNAs (snoRNAs), microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), are RNA molecules that arise from genomic regions without protein-coding ...
Jin Wang, Xiaomeng He, Christopher Corpe
doaj   +1 more source

Small nuclear RNAs and small nuclear ribonucleoprotein complexes purified from the feline placenta.

open access: yesThe Japanese Journal of Veterinary Science, 1986
Small nuclear RNAs (snRNAs) and small nuclear ribonucleoprotein particles (snRNPs) were purified from the cat placenta as an initial step in the analysis of the regulatory mechanism(s) of gene expression in the placenta. For visual observations, snRNA species including 7S, U2, U1, U4, X-I, X-II, 5S, U5, U6 and X-III were stained with acrydine orange ...
Motoo Matsuda, Takatsugu Yamada
openaire   +3 more sources

Plant snRNP Biogenesis: A Perspective from the Nucleolus and Cajal Bodies

open access: yesFrontiers in Plant Science, 2018
Small nuclear ribonucleoproteins (snRNPs) are protein–RNA complexes composed of specific snRNP-associated proteins along with small nuclear RNAs (snRNAs), which are non-coding RNA molecules abundant in the nucleus.
Misato Ohtani, Misato Ohtani
doaj   +1 more source

From early lessons to new frontiers: The worm as a treasure trove of small RNA biology

open access: yesFrontiers in Genetics, 2014
In the past twenty years, the tiny soil nematode C. elegans has provided critical insights into our understanding of the breadth of small RNA-mediated gene regulatory activities. The first microRNA was identified in C.
Elaine M. Youngman, Julie M Claycomb
doaj   +1 more source

Home - About - Disclaimer - Privacy