Results 11 to 20 of about 218,333 (309)

Weight Change Alters the Small RNA Profile of Urinary Extracellular Vesicles in Obesity

Obesity Facts, 2022
Introduction: Various kidney diseases reportedly show different urinary extracellular vesicle (EV) RNA profiles. Although obesity is one of the main causes of chronic kidney disease, the expression pattern of urinary EV RNA in obesity is uncertain.
Dughyun Choi, Sewon Kim, Jeyoung Woo, Haekyung Lee, Hyoungnae Kim, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han, Sang Hyun Kim, Ho Chan Cho, Jong-Soo Choi, Yun-Ui Bae, Soon Hyo Kwon   +12 more
doaj   +1 more source

An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes

Cell Reports, 2020
Summary: Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated regions (UTRs) to control gene expression. Using a comparative structural analysis, we examine the structure of 5′ UTRs at a global scale in the pathogenic ...
Dmitriy Ignatov, Karolis Vaitkevicius, Sylvain Durand, Laty Cahoon, Stefanie S. Sandberg, Xijia Liu, Birgitte H. Kallipolitis, Patrik Rydén, Nancy Freitag, Ciarán Condon, Jörgen Johansson   +10 more
doaj   +1 more source

Several different sequences are implicated in bloodstream-form-specific gene expression in Trypanosoma brucei.

PLoS Neglected Tropical Diseases, 2022
The parasite Trypanosoma brucei grows as bloodstream forms in mammalian hosts, and as procyclic forms in tsetse flies. In trypanosomes, gene expression regulation depends heavily on post-transcriptional mechanisms.
Tania Bishola Tshitenge, Lena Reichert, Bin Liu, Christine Clayton   +3 more
doaj   +1 more source

Untranslated Regions of a Mobile Transcript Mediate RNA Metabolism [PDF]

Plant Physiology, 2009
BEL1-like transcription factors are ubiquitous in plants and interact with KNOTTED1 types to regulate numerous developmental processes. In potato (Solanum tuberosum subsp. andigena), the BEL1-like transcription factor StBEL5 and its Knox protein partner regulate tuber formation by targeting genes that control growth.
Anjan K, Banerjee, Tian, Lin, David J, Hannapel   +2 more
openaire   +2 more sources

Investigation of Novel RNA Elements in the 3′UTR of Tobacco Necrosis Virus-D

Viruses, 2020
RNA elements in the untranslated regions of plus-strand RNA viruses can control a variety of viral processes including translation, replication, packaging, and subgenomic mRNA production.
Laura R. Newburn, Baodong Wu, K. Andrew White   +2 more
doaj   +1 more source

Structure of the 5′ Untranslated Region of Enteroviral Genomic RNA [PDF]

Journal of Virology, 2019
Enterovirus infections are responsible for human diseases, including myocarditis, pancreatitis, acute flaccid paralysis, and poliomyelitis. The virulence of these viruses depends on efficient recognition of the RNA genome by a large family of host proteins and protein synthesis factors, which in turn relies on the three-dimensional folding of the first
Mahmud, Bejan, Horn, Christopher M., Tapprich, William E.   +2 more
openaire   +2 more sources

Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response

Nature Communications, 2023
Long noncoding RNA molecules are RNA transcripts long thought to remain untranslated. In this study, the authors demonstrate that certain lncRNA can be translated into peptides that are immunogenic to CD8+ T cells and promote anti-tumour responses when ...
Wojciech Barczak, Simon M. Carr, Geng Liu, Shonagh Munro, Annalisa Nicastri, Lian Ni Lee, Claire Hutchings, Nicola Ternette, Paul Klenerman, Alexander Kanapin, Anastasia Samsonova, Nicholas B. La Thangue   +11 more
doaj   +1 more source

Discovering non-coding RNA elements in Drosophila 3' untranslated regions [PDF]

International Journal of Bioinformatics Research and Applications, 2014
The Non-Coding RNA (ncRNA) elements in the 3' Untranslated Regions (3'-UTRs) are known to participate in the genes' post-transcriptional regulations. Inferring co-expression patterns of the genes through clustering these 3'-UTR ncRNA elements will provide invaluable insights for studying their biological functions. In this paper, we propose an improved
Zhong, Cuncong, Andrews, Justen, Zhang, Shaojie   +2 more
openaire   +4 more sources

Hfq Is Necessary for Regulation by the Untranslated RNA DsrA [PDF]

Journal of Bacteriology, 2001
ABSTRACTDsrA is an 85-nucleotide, untranslated RNA that has multiple regulatory activities at 30°C. These activities include the translational regulation of RpoS and H-NS, global transcriptional regulators inEscherichia coli. Hfq is anE. coliprotein necessary for the in vitro and in vivo replication of the RNA phage Qβ.
D D, Sledjeski, C, Whitman, A, Zhang
openaire   +2 more sources

Role of noncoding RNAs and untranslated regions in cancer: A review

Medicine, 2022
Cancer is one of the most prevalent diseases worldwide, and poses a threat to human health. Noncoding RNAs (ncRNAs) constitute most transcripts, but they cannot be translated into proteins. Studies have shown that ncRNAs can act as tumor suppressors or oncogenes.
Yiping Zhang, Meiwen Yang, Shulong Yang, Fenfang Hong   +3 more
openaire   +2 more sources