Results 111 to 120 of about 3,502 (177)

A structural and biochemical comparison of Ribonuclease E homologues from pathogenic bacteria highlights species-specific properties

open access: yesScientific Reports, 2019
Regulation of gene expression through processing and turnover of RNA is a key mechanism that allows bacteria to rapidly adapt to changing environmental conditions.
Charlotte E. Mardle   +7 more
doaj   +1 more source

The DEAD-box RNA helicase CshA is required for fatty acid homeostasis in Staphylococcus aureus.

open access: yesPLoS Genetics, 2020
Staphylococcus aureus is an opportunistic pathogen that can grow in a wide array of conditions: on abiotic surfaces, on the skin, in the nose, in planktonic or biofilm forms and can cause many type of infections. Consequently, S.
Vanessa Khemici   +7 more
doaj   +1 more source

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway [PDF]

open access: yes, 2014
The pluripotency factor Lin28 blocks the expression of let-7 microRNAs (miRNAs) in undifferentiated cells during development and functions as an oncogene in a subset of cancers1.
Chang, Hao-Ming   +3 more
core   +1 more source

Recent insights into the world of dual‐function bacterial sRNAs

open access: yesWIREs RNA, Volume 15, Issue 1, January/February 2024.
Dual‐function sRNAs are fascinating riboregulators that act both as base‐pairing antisense RNAs and as peptide‐coding mRNAs, offering the possibility to control target function at different regulatory levels via RNA–RNA interactions as well as protein–protein interactions.
Sebastian Benjamin Schnoor   +2 more
wiley   +1 more source

A comprehensive study of the interactions in the B. subtilis degradosome with special emphasis on the role of the small proteins SR1P and SR7P

open access: yesMolecular Microbiology, Volume 121, Issue 1, Page 40-52, January 2024.
The RNA degradosome of B. subtilis comprises the major endoribonuclease RNase Y, RNases J1 and J2, PNPase, CshA helicase, and the glycolytic enzymes enolase and phosphofructokinase. Additionally, glyceraldehyde 3‐phosphate dehydrogenase A (GapA) is integrated under specific conditions.
Inam Ul Haq   +2 more
wiley   +1 more source

A bacterial secreted translocator hijacks riboregulators to control type III secretion in response to host cell contact.

open access: yesPLoS Pathogens, 2019
Numerous Gram-negative pathogens use a Type III Secretion System (T3SS) to promote virulence by injecting effector proteins into targeted host cells, which subvert host cell processes.
Maria Kusmierek   +8 more
doaj   +1 more source

Pentatricopeptide Motifs in the N-Terminal Extension Domain of Yeast Mitochondrial RNA Polymerase Rpo41p Are Not Essential for Its Function [PDF]

open access: yes, 2016
The core mitochondrial RNA polymerase is a single-subunit enzyme that in yeast Saccharomyces cerevisiae is encoded by the nuclear RPO41 gene. It is an evolutionary descendant of the bacteriophage RNA polymerases, but it includes an additional unconserved
Golik, Paweł, Kruszewski, Jakub
core   +1 more source

Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria [PDF]

open access: yes, 2014
The discovery of diverse codon reassignment events has demonstrated that the canonical genetic code is not universal. Studying coding reassignment at the molecular level is critical for understanding genetic code evolution, and provides clues to genetic ...
Church, George M.   +5 more
core   +1 more source

A set of dual promoter vectors for high throughput cloning, screening, and protein expression in eukaryotic and prokaryotic systems from a single plasmid [PDF]

open access: yes, 2012
BACKGROUND: The ability to produce the same recombinant protein in both prokaryotic and eukaryotic cells offers many experimental opportunities. However, the cloning of the same gene into multiple plasmids is required, which is time consuming, laborious ...
Charlotte A Williams   +3 more
core   +1 more source

The Roles Of Rhle And Hfq In Srna-Dependent Gene Regulation [PDF]

open access: yes, 2010
THE ROLES OF RHLE AND HFQ IN SRNA-DEPENDENT GENE REGULATION by ABEYKOON JAYALATH IRESHA SANDEEPANIE RATHNAYAKE DECEMBER 2010 Advisor: Dr. Andrew Feig Major: Chemistry Degree: Master of Science Bacteria are adapted to live in diverse environmental ...
Rathnayake, Abeykoon Jayalath Iresha Sandeepanie
core   +1 more source

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