Results 101 to 110 of about 3,502 (177)

Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni [PDF]

, 2012
Polynucleotide phosphorylase (PNPase), encoded by the pnp gene, is known to degrade mRNA, mediating post-transcriptional regulation and may affect cellular functions. The role of PNPase is pleiotropic. As orthologs of the two major ribonucleases (RNase E
Christopher M. Burns, Didier Chevret, Hervé Prévost, Jean M. Cappelier, Katell Rivoal, Nabila Haddad, Odile Tresse, Quentin Nonglaton   +7 more
core   +3 more sources

The Conserved Dcw Gene Cluster of R. sphaeroides Is Preceded by an Uncommonly Extended 5’ Leader Featuring the sRNA UpsM [PDF]

, 2016
Cell division and cell wall synthesis mechanisms are similarly conserved among bacteria. Consequently some bacterial species have comparable sets of genes organized in the dcw (division and cell wall) gene cluster.
Klug, Gabriele, Lechner, Marcus, Remes, Bernhard, Thoelken, Clemens, Volk, Marcel, Weber, Lennart   +5 more
core   +3 more sources

The RNA degradosome in Bacillus subtilis: identification of CshA as the major RNA helicase in the multiprotein complex [PDF]

Molecular Microbiology, 2010
SummaryIn most organisms, dedicated multiprotein complexes, called exosome or RNA degradosome, carry out RNA degradation and processing. In addition to varying exoribonucleases or endoribonucleases, most of these complexes contain a RNA helicase. In the Gram‐positive bacterium Bacillus subtilis, a RNA degradosome has recently been described; however ...
Lehnik-Habrink, Martin, Pfoertner, Henrike, Rempeters, Leonie, Pietack, Nico, Herzberg, Christina, Stuelke, Joerg   +5 more
openaire   +3 more sources

The contribution of mRNA targeting to spatial protein localization in bacteria

The FEBS Journal, Volume 291, Issue 21, Page 4639-4659, November 2024.
mRNA‐based targeting serves as a back‐up strategy for the canonical signal sequence‐based protein targeting in bacteria. While signal sequence‐based targeting depends on dedicated protein‐targeting factors, mRNAs encoding inner membrane proteins can bind directly to protein translocases.
Wenkang Shang, Elisabeth Lichtenberg, Andreea Mihaela Mlesnita, Annegret Wilde, Hans‐Georg Koch   +4 more
wiley   +1 more source

Pseudomonas aeruginosa enolase influences bacterial tolerance to oxidative stresses and virulence

Frontiers in Microbiology, 2016
Pseudomonas aeruginosa is a Gram negative opportunistic pathogenic bacterium, which causes acute and chronic infections. Upon entering host, bacteria alter global gene expression to adapt to host environment and avoid clearance by host.
Yuding Weng, Fei Chen, Yiwei Liu, Qiang Zhao, Xiaolei Pan, Chang Liu, Ronghao Chen, Zhihui Cheng, Shouguang Jin, Shouguang Jin, Yongxin Jin, Weihui Wu   +11 more
doaj   +1 more source

Membrane-association of mRNA decapping factors is independent of stress in budding yeast [PDF]

, 2016
Recent evidence has suggested that the degradation of mRNA occurs on translating ribosomes or alternatively within RNA granules called P bodies, which are aggregates whose core constituents are mRNA decay proteins and RNA.
A Hunt, A van Hoof, A-C Gavin, AE Frazier, AH Becker, AS Madrid, AS Spirin, C Kilchert, CB Brachmann, CJ Beckham, CJ Decker, D Teixeira, DA Mangus, DJ Gibbings, E Vergés, GM Rubin, H Strahl, H Zhang, J Coller, J LaCava, J Schindelin, J-H Yoon, JA Boon den, JA Toretsky, JE Hesketh, JE Wilhelm, K Shahbabian, KA Burke, KJ Bandyra, KJ Holmes, KM Kuhn, L Hatfield, L Huang, L Stalder, L Stalder, LEA Holmes, M Brengues, MP Ashe, N Cougot, R Parker, S Ghaemmaghami, S Huch, S Jagannathan, S Jonas, S Kadaba, S Kroschwald, T Nissan, T Nissan, T Sweet, TJ Sweet, U Sheth, V Balagopal, V Jouannet, V Khemici, V Pelechano, W Hu, W-K Huh, X Wang, Y Lin, Y Uesono, YS Lee, Z Li   +61 more
core   +1 more source

Biomolecular Condensates: From Bacterial Compartments to Incubator Spaces of Emergent Chemical Systems in Matter‐to‐Life Transitions

ChemSystemsChem, Volume 6, Issue 4, July 2024.
This review examines discoveries of biomolecular condensates as compartments in bacteria. Insights from bacterial cell biology and systems chemistry reveal intricate connections between chemical reactions and the control of condensate phase separation.
Wade E. Schnorr, W. Seth Childers
wiley   +1 more source

Elucidation of the Photorhabdus temperata Genome and Generation of a Transposon Mutant Library To Identify Motility Mutants Altered in Pathogenesis [PDF]

, 2015
The entomopathogenic nematode Heterorhabditis bacteriophora forms a specific mutualistic association with its bacterial partner Photorhabdus temperata.
Abebe-Akele, Feseha, Bullock, Hannah, Durakovic, Umjia, Gately, Jon, Hurst, Sheldon G., IV, Jackobeck, Ryan, Janicki, Erik, Michaels, Brandye, Rowedder, Holli, Tisa, Louis S.   +9 more
core   +2 more sources

Polyadenylation Promotes Degradation of 3′-Structured RNA by theEscherichia coli mRNA Degradosome in Vitro [PDF]

Journal of Biological Chemistry, 1999
Polyadenylation contributes to the destabilization of bacterial mRNA. We have investigated the role of polyadenylation in the degradation of RNA by the purified Escherichia coli degradosome in vitro. RNA molecules with 3'-ends incorporated into a stable stem-loop structure could not readily be degraded by purified polynucleotide phosphorylase or by the
E, Blum, A J, Carpousis, C F, Higgins
openaire   +2 more sources

Escherichia coli strains with precise domain deletions in the ribonuclease RNase E can achieve greatly enhanced levels of membrane protein production

Protein Science, Volume 33, Issue 2, February 2024.
Abstract Escherichia coli is one of the most widely utilized hosts for production of recombinant membrane proteins (MPs). Bacterial MP production, however, is usually accompanied by severe toxicity and low‐level volumetric accumulation. In previous work, we had discovered that co‐expression of RraA, an inhibitor of the RNA‐degrading activity of RNase E,
Eleni Vasilopoulou, Tania Chroumpi, Georgios Skretas   +2 more
wiley   +1 more source