Results 81 to 90 of about 3,502 (177)

Diamide-based screening method for the isolation of improved oxidative stress tolerance phenotypes in Bacillus mutant libraries

open access: yesMicrobiology Spectrum, 2023
The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules.
Jonathan Walgraeve   +6 more
doaj   +1 more source

Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS

open access: yesPROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor   +3 more
wiley   +1 more source

Simulating bacterial transcription and translation in a stochastic pi-calculus [PDF]

open access: yes, 2006
International audienceStochastic simulation of genetic networks based on models in the stochastic pi-calculus is a promising recent approach. This paper contributes an extensible model of the central mechanisms of gene ex- pression i.e. transcription and
Kuttler, Celine
core   +1 more source

Maturation of Polycistronic mRNAs by the Endoribonuclease RNase Y and Its Associated Y-Complex in Bacillus Subtilis [PDF]

open access: yes, 2018
Endonucleolytic cleavage within polycistronic mRNAs can lead to differential stability, and thus discordant abundance, among cotranscribed genes. RNase Y, the major endonuclease for mRNA decay in Bacillus subtilis, was originally identified for its ...
DeLoughery, Aaron   +3 more
core   +1 more source

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

open access: yesMolecular Microbiology, Volume 125, Issue 2, Page 108-122, February 2026.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke   +3 more
wiley   +1 more source

Metabolic Origin, Role and Fate of the Denaturant Guanidine

open access: yesMicrobial Biotechnology, Volume 18, Issue 11, November 2025.
The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin   +3 more
wiley   +1 more source

CRP-cAMP mediates silencing of Salmonella virulence at the post-transcriptional level [PDF]

open access: yes, 2018
Invasion of epithelial cells by Salmonella enterica requires expression of genes located in the pathogenicity island I (SPI-1). The expression of SPI-1 genes is very tightly regulated and activated only under specific conditions.
Balsalobre, Carlos   +6 more
core   +4 more sources

Synthesis of empty bacterial microcompartments, directed organelle protein incorporation, and evidence of filament-associated organelle movement [PDF]

open access: yes, 2010
Compartmentalization is an important process, since it allows the segregation of metabolic activities and, in the era of synthetic biology, represents an important tool by which defined microenvironments can be created for specific metabolic functions ...
Bhella, D.   +6 more
core   +2 more sources

Global Lactylome Reveals Lactylation‐Dependent Mechanisms Underlying CXC Motif Chemokine Ligand 12 Expression in Pulmonary Endothelium During Acute Respiratory Distress Syndrome

open access: yesMedComm, Volume 6, Issue 9, September 2025.
In quiescent PECs, Eno1 binds to the 3′ UTR of CXCL12 mRNA to prevent translation. Following activation, lactate is accumulated and then mediates an increase in lysine lactylation. Eno1, a substrate in this modification, releases bound CXCL12 mRNA upon lactylation to promote translation. Meanwhile, the activity of Eno1 as a glycolytic enzyme increases,
Xu Liu   +5 more
wiley   +1 more source

The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C

open access: yesBMC Microbiology, 2012
Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas   +4 more
doaj   +1 more source

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