Results 61 to 70 of about 3,502 (177)

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. [PDF]

PLoS ONE, 2013
Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds
Hongjiang Wu, Hong Sun, Xuehai Liang, Walt F Lima, Stanley T Crooke   +4 more
doaj   +1 more source

An effort to make sense of antisense transcription in bacteria [PDF]

, 2012
Analysis of bacterial transcriptomes have shown the existence of a genome-wide process of overlapping transcription due to the presence of antisense RNAs, as well as mRNAs that overlapped in their entire length or in some portion of the 5'- and 3'-UTR ...
Gingeras, T. R., Lasa, I., Toledo-Arana, A.   +2 more
core   +1 more source

Controlling the mitochondrial antisense – role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance

Molecular & Cellular Oncology, 2018
Transcription of the human mitochondrial genome produces a vast amount of non-coding antisense RNAs. These RNA species can form G-quadraplexes (G4), which affect their decay. We found that the mitochondrial degradosome, a complex of RNA helicase SUPV3L1 (
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny   +8 more
doaj   +1 more source

Examining the Protein Interactome and Subcellular Localization of RNase J2 Complexes in Streptococcus mutans

Frontiers in Microbiology, 2019
Regulated RNA turnover is vital for the control of gene expression in all cellular life. In Escherichia coli, this process is largely controlled by a stable degradosome complex containing RNase E and a variety of additional enzymes.
Rong Mu, Pushkar Shinde, Zhengzhong Zou, Jens Kreth, Jens Kreth, Justin Merritt, Justin Merritt   +6 more
doaj   +1 more source

RNA chaperones buffer deleterious mutations in E. coli [PDF]

, 2015
International ...
Bae, Barrick, Bhaskaran, Bogumil, Bradford, Burga, Collins, Death, Downs, Elles, Fares, Hartl, Herschlag, Hilier, Hunger, Jarmoskaite, Jiang, Khemici, Lenski, Lenski, Lind, Lorenz, Mohr, Pan, Plotkin, Py, Queitsch, Quinlan, Rohner, Russell, Rutherford, Sawitzke, Sniegowski, Tenaillon, Tokuriki, Turner, Vallenet, Vanzo, Warnecke, Williams   +39 more
core   +2 more sources

Biophysical characterization of the Escherichia coli RNA degradosome

, 2022
In Escherichia coli, post-transcriptional regulation is a tightly controlled process facilitated by a multi-enzyme complex, the RNA degradosome. The core components of the RNA degradosome consist of the endoribonuclease RNase E, the DEAD-box helicase RhlB, the glycolytic enzyme enolase, and the exoribonuclease PNPase. The main scaffold component of the
openaire   +1 more source

Riboregulation in the Major Gastric Pathogen Helicobacter pylori

Frontiers in Microbiology, 2021
Helicobacter pylori is a Gram-negative bacterial pathogen that colonizes the stomach of about half of the human population worldwide. Infection by H.
Alejandro Tejada-Arranz, Alejandro Tejada-Arranz, Hilde De Reuse   +2 more
doaj   +1 more source

Genome-Wide Study of mRNA Degradation and Transcript Elongation in Escherichia coli [PDF]

, 2015
An essential part of gene expression is the coordination of RNA synthesis and degradation, which occurs in the same cellular compartment in bacteria.
Chen, Huiyi, Ge, Hao, Shiroguchi, Katsuyuki, Xie, Xiaoliang Sunney   +3 more
core   +2 more sources

A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function

Cell Reports, 2015
The mitochondrial genome relies heavily on post-transcriptional events for its proper expression, and misregulation of this process can cause mitochondrial genetic diseases in humans.
Alexis A. Jourdain, Mirko Koppen, Christopher D. Rodley, Kinsey Maundrell, Naïg Gueguen, Pascal Reynier, Adela M. Guaras, José A. Enriquez, Paul Anderson, Maria Simarro, Jean-Claude Martinou   +10 more
doaj   +1 more source

Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity

eLife, 2022
CRISPR-Cas systems are a family of adaptive immune systems that use small CRISPR RNAs (crRNAs) and CRISPR-associated (Cas) nucleases to protect prokaryotes from invading plasmids and viruses (i.e., phages).
Lucy Chou-Zheng, Asma Hatoum-Aslan
doaj   +1 more source