Results 51 to 60 of about 738,204 (145)
Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity
eLife, 2022 CRISPR-Cas systems are a family of adaptive immune systems that use small CRISPR RNAs (crRNAs) and CRISPR-associated (Cas) nucleases to protect prokaryotes from invading plasmids and viruses (i.e., phages).
Lucy Chou-Zheng, Asma Hatoum-Aslan
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The FEBS Journal, Volume 293, Issue 12, Page 3588-3600, June 2026.Polyphosphate interaction with Hfq and RNA drives phase separation and amyloid self‐assembly, uncovering a previously unrecognized role for polyP in bacterial stress responses. Our findings reveal new insights into the molecular mechanisms of RNA‐mediated phase separation, highlighting the role of polyP as a key modulator of this process. Polyphosphate
Kevin Mosca +5 more
wiley +1 more source
Spatial organization shapes the turnover of a bacterial transcriptome
eLife, 2016 Spatial organization of the transcriptome has emerged as a powerful means for regulating the post-transcriptional fate of RNA in eukaryotes; however, whether prokaryotes use RNA spatial organization as a mechanism for post-transcriptional regulation ...
Jeffrey R Moffitt +4 more
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BMC Genomics, 2021 Background The polynucleotide phosphorylase (PNPase) is conserved among both Gram-positive and Gram-negative bacteria. As a core part of the Escherichia coli degradosome, PNPase is involved in maintaining proper RNA levels within the bacterial cell.
Daniel-Timon Spanka +2 more
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Formation of a stable RNase Y-RicT (YaaT) complex requires RicA (YmcA) and RicF (YlbF)
mBio, 2023 In Bacillus subtilis, the RicT (YaaT), RicA (YmcA), and RicF (YlbF) proteins, which form a stable ternary complex, are needed together with RNase Y (Rny) to cleave and thereby stabilize several key transcripts encoding enzymes of intermediary metabolism.
Eugenie Dubnau +2 more
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Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
PROTEOMICS, Volume 26, Issue 5, Page 27-36, May 2026.ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Characterization of RNA degradosome from E. coli with mutant polynucleotide phosphorylase
, 2006 The RNA degradosome is a bacterial protein machine devoted to RNA turnover. Degradosomes and related complexes have been described in Escherichia coli and other prokaryotes as well as in eukaryotes. The integral components of the E.
F. Briani +4 more
core +4 more sources
Genes important for catalase activity in Enterococcus faecalis. [PDF]
PLoS ONE, 2012 Little in general is known about how heme proteins are assembled from their constituents in cells. The Gram-positive bacterium Enterococcus faecalis cannot synthesize heme and does not depend on it for growth.
Michael Baureder, Lars Hederstedt
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Microbiology Spectrum, 2023 The bacterium Bacillus subtilis is of high importance both as a model organism for Gram-positive bacteria and as an industrial workhorse in the production of biomolecules.
Jonathan Walgraeve +6 more
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Molecular Microbiology, Volume 125, Issue 2, Page 108-122, February 2026.Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke +3 more
wiley +1 more source