Results 51 to 60 of about 3,502 (177)

A eukaryotic-like 3′ untranslated region in Salmonella enterica hilD mRNA [PDF]

, 2014
Long 3' untranslated regions (3'UTRs) are common in eukaryotic mRNAs. In contrast, long 3'UTRs are rare in bacteria, and have not been characterized in detail.
Casadesús Pursals, Josep, López Garrido, Javier, Puerta Fernández, Elena   +2 more
core   +1 more source

Unraveling new roles for minor components of the E. coli RNA degradosome [PDF]

RNA Biology, 2009
Endoribonuclease E, 3'-5' exoribonuclease polynucleotide phosphorylase, RhlB RNA helicase and enolase form a multienzyme complex (the "degradosome") playing an important role in RNA processing and decay in Escherichia coli. Although a number of proteins that occasionally co-purify with the E.
Vladimir R, Kaberdin, Sue, Lin-Chao
openaire   +2 more sources

Polyphosphate - an ancient energy source and active metabolic regulator [PDF]

, 2011
There are a several molecules on Earth that effectively store energy within their covalent bonds, and one of these energy-rich molecules is polyphosphate.
Lucia Achbergerová, Jozef Nahálka
core   +1 more source

The Sole DEAD-Box RNA Helicase of the Gastric Pathogen Helicobacter pylori Is Essential for Colonization

mBio, 2018
Present in every kingdom of life, generally in multiple copies, DEAD-box RNA helicases are specialized enzymes that unwind RNA secondary structures. They play major roles in mRNA decay, ribosome biogenesis, and adaptation to cold temperatures.
Lamya El Mortaji, Sylvie Aubert, Eloïse Galtier, Christine Schmitt, Karine Anger, Yulia Redko, Yves Quentin, Hilde De Reuse   +7 more
doaj   +1 more source

The first small-molecule inhibitors of members of the ribonuclease E family [PDF]

, 2015
The Escherichia coli endoribonuclease RNase E is central to the processing and degradation of all types of RNA and as such is a pleotropic regulator of gene expression.
A Danchin, A Koul, AJ Callaghan, AJ Callaghan, AJ Callaghan, AJ Carpousis, AJ Carpousis, AP Walsh, AR Subramanian, BK Ghora, BK Mohanty, BK Shoichet, C Condon, C Condon, C Dye, CM Arraiano, D Apirion, D Suck, GA Mackie, JE Clarke, K Lee, KH Bleicher, KJ McDowall, KJ McDowall, L Kime, L Kime, M Kuwano, M Ono, M Wachi, MC Ow, MHJ Seifert, MJ Marcaida, N Guex, O Guner, O Zelenko, SM Garrey, SS Jourdan, V Khemici, VJ Gillet, VR Kaberdin, XQ Jiang, Y Redko, Z Zsoldos, ZW Li   +43 more
core   +4 more sources

Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC

BMC Genomics, 2012
Background Bacterial genomes displaying a strong bias between the leading and the lagging strand of DNA replication encode two DNA polymerases III, DnaE and PolC, rather than a single one.
Engelen Stefan, Vallenet David, Médigue Claudine, Danchin Antoine   +3 more
doaj   +1 more source

Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli [PDF]

, 2014
Escherichia coli endoribonuclease E has a major influence on gene expression. It is essential for the maturation of ribosomal and transfer RNA as well as the rapid degradation of messenger RNA.
Clarke, JE, Kime, L, McDowall, KJ, Romero Alvarez, D   +3 more
core   +1 more source

Global analysis of Escherichia coli RNA degradosome function using DNA microarrays [PDF]

Proceedings of the National Academy of Sciences, 2004
RNase E, an essential endoribonuclease of Escherichia coli , interacts through its C-terminal region with multiple other proteins to form a complex termed the RNA degradosome. To investigate the degradosome's proposed role as an RNA decay machine, we used DNA microarrays to globally assess alterations in the steady ...
Jonathan A, Bernstein, Pei-Hsun, Lin, Stanley N, Cohen, Sue, Lin-Chao   +3 more
openaire   +2 more sources

Inflammatory mitochondrial nucleic acids as drivers of pathophysiology

, 2023
Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Christian G. Peace, Alexander Hooftman, Dylan G. Ryan   +2 more
wiley   +1 more source

The exoribonuclease Polynucleotide Phosphorylase influences the virulence and stress responses of yersiniae and many other pathogens

Frontiers in Cellular and Infection Microbiology, 2013
Microbes are incessantly challenged by both biotic and abiotic stressors threatening their existence. Therefore, bacterial pathogens must possess mechanisms to successfully subvert host immune defenses as well as overcome the stress associated with host ...
Jason A. Rosenzweig, Ashok K Chopra
doaj   +1 more source