Results 31 to 40 of about 738,204 (145)
Nature Communications, 2023 Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA degradosome, plays an essential role in global mRNA decay.
Luyao Bao +15 more
doaj +1 more source
Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA
Frontiers in Molecular Biosciences, 2023 The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome.
Heidi Zetzsche +2 more
doaj +1 more source
The BR-body proteome contains a complex network of protein-protein and protein-RNA interactions
Cell Reports, 2023 Summary: Bacterial ribonucleoprotein bodies (BR-bodies) are non-membrane-bound structures that facilitate mRNA decay by concentrating mRNA substrates with RNase E and the associated RNA degradosome machinery.
Vidhyadhar Nandana +16 more
doaj +1 more source
Editosome Accessory Factors KREPB9 and KREPB10 in Trypanosoma brucei [PDF]
, 2012 Multiprotein complexes, called editosomes, catalyze the uridine insertion and deletion RNA editing that forms translatable mitochondrial mRNAs in kinetoplastid parasites.
Acestor, Nathalie +5 more
core +1 more source
mSystems, 2023 Both prokaryotic and eukaryotic RNAs can be 5′-capped by the metabolite nicotinamide adenine dinucleotide (NAD). Nudix hydrolases, such as bacterial NudC, specifically remove NAD-caps; however, the molecular and cellular functions of these ...
Milda Mickutė +10 more
doaj +1 more source
SR7 – a dual-function antisense RNA from Bacillus subtilis
RNA Biology, 2021 Here, we describe SR7, a dual-function antisense RNA encoded on the Bacillus subtilis chromosome. This RNA was earlier described as SigB-dependent regulatory RNA S1136 and reported to reduce the amount of the small ribosomal subunit under ethanol stress.
Inam Ul Haq +2 more
doaj +1 more source
Analysis of the RNA degradosome complex from a Marine Vibrio species [PDF]
, 2010 The RNA degradosome is a conglomerate of proteins responsible for the degradation of most mRNA transcripts in the prokaryotic cell. The present work was motivated by the need to better understand whether the RNA degradosome in Vibrio angustum S14 is ...
Erce, Melissa Angelica
core +1 more source
mBio, 2018 Present in every kingdom of life, generally in multiple copies, DEAD-box RNA helicases are specialized enzymes that unwind RNA secondary structures. They play major roles in mRNA decay, ribosome biogenesis, and adaptation to cold temperatures.
Lamya El Mortaji +7 more
doaj +1 more source
Inflammatory mitochondrial nucleic acids as drivers of pathophysiology
, 2023 Clinical and Translational Medicine, Volume 13, Issue 9, September 2023.
Christian G. Peace +2 more
wiley +1 more source
Distinct co-evolution patterns of genes associated to DNA polymerase III DnaE and PolC
BMC Genomics, 2012 Background Bacterial genomes displaying a strong bias between the leading and the lagging strand of DNA replication encode two DNA polymerases III, DnaE and PolC, rather than a single one.
Engelen Stefan +3 more
doaj +1 more source