Results 11 to 20 of about 738,204 (145)

The social fabric of the RNA degradosome [PDF]

Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2013
International audienceBacterial transcripts each have a characteristic half-life, suggesting that the processes of RNA degradation work in an active and selective manner.
Agamemnon J Carpousis, Marie Bouvier, Ben Luisi   +2 more
exaly   +5 more sources

Association of the Cold Shock DEAD-Box RNA Helicase RhlE to the RNA Degradosome in Caulobacter crescentus. [PDF]

Journal of Bacteriology, 2017
In diverse bacterial lineages, multienzyme assemblies have evolved that are central elements of RNA metabolism and RNA-mediated regulation. The aquatic Gram-negative bacterium Caulobacter crescentus , which has been a model system
Alexandre M Vicente, Steven W Hardwick, Ricardo R Mazzon   +2 more
exaly   +3 more sources

Multi-scale ensemble properties of the Escherichia coli RNA degradosome. [PDF]

Mol Microbiol, 2022
In organisms from all domains of life, multi-enzyme assemblies play central roles in defining transcript lifetimes and facilitating RNA-mediated regulation of gene expression.
Dendooven T, Paris G, Shkumatov AV, Islam MS, Burt A, Kubańska MA, Yang TY, Hardwick SW, Luisi BF.   +8 more
europepmc   +5 more sources

The RNA degradosome promotes tRNA quality control through clearance of hypomodified tRNA [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2019
Matthew Waldor, Satoshi Kimura
exaly   +2 more sources

Cooperation of regulatory RNA and the RNA degradosome in transcript surveillance. [PDF]

Nucleic Acids Res
The ompD transcript, encoding an outer membrane porin in Salmonella, harbors a controlling element in its coding region that base-pairs imperfectly with a 'seed' region of the small regulatory RNA (sRNA) MicC.
Bandyra KJ, Fröhlich KS, Vogel J, Rodnina M, Goyal A, Luisi BF.   +5 more
europepmc   +26 more sources

Proteomic and transcriptomic experiments reveal an essential role of RNA degradosome complexes in shaping the transcriptome of Mycobacterium tuberculosis [PDF]

Nucleic Acids Research, 2019
Emilia Niemiec, Andrzej Dziembowski, Przemysław Płociński   +2 more
exaly   +2 more sources

Polyribosome-Dependent Clustering of Membrane-Anchored RNA Degradosomes To Form Sites of mRNA Degradation in Escherichia coli

mBio, 2021
Here, we show that RNase E, RhlB, and PNPase act together as components of the multienzyme RNA degradosome in polyribosome-dependent clustering to form puncta on the inner cytoplasmic membrane.
Lina Hamouche, Leonora Poljak, Agamemnon J. Carpousis   +2 more
doaj   +1 more source

The DEAD-box RNA helicase RhlB is required for efficient RNA processing at low temperature in Caulobacter

Microbiology Spectrum, 2023
The RNA helicases from the DEAD-box family participate in several biochemical processes, with special relevance in the assembly of ribosome ribonucleoparticles and in RNA turnover as part of the multi-enzymatic RNA degradosome complex.
Hugo L. de Araújo, Beatriz A. Picinato, Alan P. R. Lorenzetti, Nisansala S. Muthunayake, I. W. Rathnayaka-Mudiyanselage, Naara M. dos Santos, Jared Schrader, Tie Koide, Marilis V. Marques   +8 more
doaj   +1 more source

Biophysical characterization of the Escherichia coli RNA degradosome [PDF]

, 2022
In Escherichia coli, post-transcriptional regulation is a tightly controlled process facilitated by a multi-enzyme complex, the RNA degradosome. The core components of the RNA degradosome consist of the endoribonuclease RNase E, the DEAD-box helicase ...

core   +2 more sources

Moonlighting in Bacillus subtilis: The Small Proteins SR1P and SR7P Regulate the Moonlighting Activity of Glyceraldehyde 3-Phosphate Dehydrogenase A (GapA) and Enolase in RNA Degradation

Microorganisms, 2021
Moonlighting proteins are proteins with more than one function. During the past 25 years, they have been found to be rather widespread in bacteria. In Bacillus subtilis, moonlighting has been disclosed to occur via DNA, protein or RNA binding or protein ...
Inam Ul Haq, Sabine Brantl
doaj   +1 more source