Results 41 to 50 of about 738,204 (145)

The exoribonuclease Polynucleotide Phosphorylase influences the virulence and stress responses of yersiniae and many other pathogens

Frontiers in Cellular and Infection Microbiology, 2013
Microbes are incessantly challenged by both biotic and abiotic stressors threatening their existence. Therefore, bacterial pathogens must possess mechanisms to successfully subvert host immune defenses as well as overcome the stress associated with host ...
Jason A. Rosenzweig, Ashok K Chopra
doaj   +1 more source

Association of the Cold Shock DEAD-Box RNA Helicase RhlE to the RNA Degradosome in $\textit{Caulobacter crescentus}$ [PDF]

, 2017
In diverse bacterial lineages, multienzyme assemblies have evolved that are central elements of RNA metabolism and RNA-mediated regulation. The aquatic Gram-negative bacterium $\textit{Caulobacter crescentus}$, which has been a model system for studying ...

core   +3 more sources

The E.coli RNA degradosome analysis of molecular chaperones and enolase [PDF]

, 2010
Normal mRNA turnover is essential for genetic regulation within cells. The E. coli RNA degradosome, a large multi-component protein complex which originates through specific protein interactions, has been referred to as the “RNA decay machine” and is ...
Burger, Adélle
core   +1 more source

Controlling the mitochondrial antisense – role of the SUV3-PNPase complex and its co-factor GRSF1 in mitochondrial RNA surveillance

Molecular & Cellular Oncology, 2018
Transcription of the human mitochondrial genome produces a vast amount of non-coding antisense RNAs. These RNA species can form G-quadraplexes (G4), which affect their decay. We found that the mitochondrial degradosome, a complex of RNA helicase SUPV3L1 (
Zbigniew Pietras, Magdalena A. Wojcik, Lukasz S. Borowski, Maciej Szewczyk, Tomasz M. Kulinski, Dominik Cysewski, Piotr P. Stepien, Andrzej Dziembowski, Roman J. Szczesny   +8 more
doaj   +1 more source

Examining the Protein Interactome and Subcellular Localization of RNase J2 Complexes in Streptococcus mutans

Frontiers in Microbiology, 2019
Regulated RNA turnover is vital for the control of gene expression in all cellular life. In Escherichia coli, this process is largely controlled by a stable degradosome complex containing RNase E and a variety of additional enzymes.
Rong Mu, Pushkar Shinde, Zhengzhong Zou, Jens Kreth, Jens Kreth, Justin Merritt, Justin Merritt   +6 more
doaj   +1 more source

Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. [PDF]

PLoS ONE, 2013
Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds
Hongjiang Wu, Hong Sun, Xuehai Liang, Walt F Lima, Stanley T Crooke   +4 more
doaj   +1 more source

The regulatory protein RraA modulates RNA-binding and helicase activities of the E. coli RNA degradosome

, 2010
The Escherichia coli endoribonuclease RNase E is an essential enzyme having key roles in mRNA turnover and the processing of several structured RNA precursors, and it provides the scaffold to assemble the multienzyme RNA degradosome.
Tsai, Y., Callaghan, AJ, Górna, MW, Pietras, Z, Luisi, BF, Hernández, H, Pietras, Z., Callaghan, Anastasia, Hernandez, H., Luisi, B., Tsai, YC, Gorna, M., Robinson, CV, Robinson, Carol V.   +13 more
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A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function

Cell Reports, 2015
The mitochondrial genome relies heavily on post-transcriptional events for its proper expression, and misregulation of this process can cause mitochondrial genetic diseases in humans.
Alexis A. Jourdain, Mirko Koppen, Christopher D. Rodley, Kinsey Maundrell, Naïg Gueguen, Pascal Reynier, Adela M. Guaras, José A. Enriquez, Paul Anderson, Maria Simarro, Jean-Claude Martinou   +10 more
doaj   +1 more source

Riboregulation in the Major Gastric Pathogen Helicobacter pylori

Frontiers in Microbiology, 2021
Helicobacter pylori is a Gram-negative bacterial pathogen that colonizes the stomach of about half of the human population worldwide. Infection by H.
Alejandro Tejada-Arranz, Alejandro Tejada-Arranz, Hilde De Reuse   +2 more
doaj   +1 more source

Quality control of ribosome assembly by the membrane-attached RNA degradosome.

, 2023
Cartoon depicting the synthesis of rRNA in the nucleoid, the release of early intermediates in ribosome assembly from nucleoid, maturation of late intermediates in the cytoplasm, and trimming of 17S and 9S rRNA by the membrane-attached RNA degradosome ...
Odile Burlet-Schlitz (14334426), Laurence Girbal (389237), Carine Froment (848571), Lina Hamouche (14334429), Lydia Hadjeras (13235616), Muriel Cocaign-Bousquet (255722), Agamemnon J. Carpousis (14334432), Leonora Poljak (688989), Isabelle Canal (14334420), Quentin Morin-Ogier (14334423), Marie Bouvier (260008)   +10 more
core   +1 more source