Results 211 to 220 of about 768,185 (263)

Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan, Michael P. Ryan, Sarah Hudson, Damien Thompson   +3 more
wiley   +1 more source

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

Molecular Carcinogenesis, Volume 65, Issue 10, Page 1343-1350, October 2026.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla, Rasha Alfattal, Susan L. McGovern, Shaan M. Raza, Franco DeMonte, Leomar Y. Ballester, Chirag B. Patel, Carlos Kamiya‐Matsuoka   +7 more
wiley   +1 more source

Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes. [PDF]

Nat Commun
Fujita KI, Ito M, Irie M, Harada K, Fujiwara N, Ikeda Y, Yoshioka H, Yamazaki T, Kojima M, Mikami B, Mayeda A, Masuda S.   +11 more
europepmc   +1 more source

Targeting the DNA Damage Response in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Targeting the DNA damage response (DDR) reshapes both tumor vulnerability and antitumor immunity. DNA lesions and DDR inhibitors can promote cytosolic nucleic‐acid sensing, antigen presentation, and immune activation, but can also induce adaptive immune escape.
Yihuan Qiao, Boyu Kang, Jian Zhang, Rui Zhang, Jipeng Li   +4 more
wiley   +1 more source

Application of Omics Technologies for Cowpea Improvement

Plant-Environment Interactions, Volume 7, Issue 5, October 2026.
ABSTRACT Cowpea (Vigna unguiculata) is a vital crop for food security, nutrition, and climate resilience in sub‐Saharan African and other semi‐arid regions. However, its improvement is constrained by the complexity of polygenic traits such as drought tolerance, pest resistance, and seed quality.
Junior S. Kamara, Festus O. Olasupo, Abdoul‐Razak Oumarou Mahamane, Katleho S. Selele   +3 more
wiley   +1 more source

Discrete roles of RNA helicases in human male germline and spermatogenesis. [PDF]

J Appl Genet, 2020
Tutak K, Rozwadowska N.
europepmc   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1644-1657, October 2026.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

General and Target-Specific DExD/H RNA Helicases in Eukaryotic Translation Initiation. [PDF]

Int J Mol Sci, 2020
Shen L, Pelletier J.
europepmc   +1 more source

Thiazolidine‐2,4‐dione and Thiazole Derivatives as Privileged Structures for Dengue Virus: A Review of Medicinal Chemistry Aspects

ChemistrySelect, Volume 11, Issue 37, 6 October 2026.
This graphical abstract summarizes thiazole, thiazolidine‐2,4‐dione, and hybrid compounds investigated as antiviral candidates against dengue virus. Representative structures and reported potencies are presented in the context of DENV serotypes. Proposed molecular targets include NS2B–NS3 protease and NS5.
Pedro César de Souza, Thaynara Paula Warren Bezerra, Matheus Vinicius Guimarães de Melo, Thayná da Silva Barros, Matheus Italo da Conceição, Michelle Melgarejo da Rosa, Moacyr Jesus Barreto de Melo Rêgo   +6 more
wiley   +1 more source

Host cellular RNA helicases regulate SARS-CoV-2 infection

, 2021
Ariumi Y.
europepmc   +1 more source