Results 21 to 30 of about 1,270,992 (292)

General and Target-Specific DExD/H RNA Helicases in Eukaryotic Translation Initiation. [PDF]

open access: yesInt J Mol Sci, 2020
DExD (DDX)- and DExH (DHX)-box RNA helicases, named after their Asp-Glu-x-Asp/His motifs, are integral to almost all RNA metabolic processes in eukaryotic cells.
Shen L, Pelletier J.
europepmc   +2 more sources

The composition and unrevealed immune role of non-RLR DExD/H box RNA helicases in fish [PDF]

open access: yesComparative Immunology Reports
The large superfamily of DExD/H box RNA helicases are involved in various life processes, such as RNA metabolism, transcriptional regulation, translation, tumorigenesis, cell cycle, and viral infection, and RIG-like receptors (RLRs) in the superfamily ...
Shan Nan Chen, Xue Yun Peng, Pin Nie
doaj   +2 more sources

Biological functions of DEAD/DEAH-box RNA helicases in health and disease. [PDF]

open access: yesNat Immunol, 2022
Andrisani O   +7 more
europepmc   +2 more sources

DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer [PDF]

open access: yesGenes and Diseases, 2023
In the era of advancement, the entire world continues to remain baffled by the increased rate of progression of cancer. There has been an unending search for novel therapeutic targets and prognostic markers to curb the oncogenic scenario.
Shaheda Tabassum, Mrinal K. Ghosh
doaj   +2 more sources

The expanding functions of cellular helicases: the tombusvirus RNA replication enhancer co-opts the plant eIF4AIII-like AtRH2 and the DDX5-like AtRH5 DEAD-box RNA helicases to promote viral asymmetric RNA replication.

open access: yesPLoS Pathogens, 2014
Replication of plus-strand RNA viruses depends on recruited host factors that aid several critical steps during replication. Several of the co-opted host factors bind to the viral RNA, which plays multiple roles, including mRNA function, as an assembly ...
Nikolay Kovalev, Peter D Nagy
doaj   +2 more sources

The DDX5/Dbp2 subfamily of DEAD-box RNA helicases. [PDF]

open access: yesWiley Interdiscip Rev RNA, 2019
The mammalian DEAD‐box RNA helicase DDX5, its paralog DDX17, and their orthologs in Saccharomyces cerevisiae and Drosophila melanogaster, namely Dbp2 and Rm62, define a subfamily of DEAD‐box proteins.
Xing Z, Ma WK, Tran EJ.
europepmc   +2 more sources

Coupling between the DEAD-box RNA helicases Ded1p and eIF4A

open access: yeseLife, 2016
Eukaryotic translation initiation involves two conserved DEAD-box RNA helicases, eIF4A and Ded1p. Here we show that S. cerevisiae eIF4A and Ded1p directly interact with each other and simultaneously with the scaffolding protein eIF4G.
Zhaofeng Gao   +7 more
doaj   +2 more sources

The RNA helicases AtMTR4 and HEN2 target specific subsets of nuclear transcripts for degradation by the nuclear exosome in Arabidopsis thaliana.

open access: yesPLoS Genetics, 2014
The RNA exosome is the major 3'-5' RNA degradation machine of eukaryotic cells and participates in processing, surveillance and turnover of both nuclear and cytoplasmic RNA.
Heike Lange   +13 more
doaj   +2 more sources

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