Results 31 to 40 of about 1,270,992 (292)
ATPase cycle and DNA unwinding kinetics of RecG helicase [PDF]
, 2012 The superfamily 2 bacterial helicase, RecG, is a monomeric enzyme with a role in DNA repair by reversing stalled replication forks. The helicase must act specifically and rapidly to prevent replication fork collapse. We have shown that RecG binds tightly
Powell, Ben +2 more
core +16 more sources
Cancer Research, 2022 DEAD-box RNA helicases belong to a large group of RNA processing factors and play vital roles unwinding RNA helices and in ribosomal RNA biogenesis. Emerging evidence indicates that RNA helicases are associated with genome stability, yet the mechanisms ...
Jinru Xie +16 more
semanticscholar +1 more source
Targeting RNA helicases in cancer: The translation trap. [PDF]
Biochim Biophys Acta Rev Cancer, 2017 Heerma van Voss MR +2 more
europepmc +2 more sources
Regulation of DEAH-box RNA helicases by G-patch proteins
Biological chemistry, 2021 RNA helicases of the DEAH/RHA family form a large and conserved class of enzymes that remodel RNA protein complexes (RNPs) by translocating along the RNA.
K. Bohnsack +3 more
semanticscholar +1 more source
Helicase: A genetic tool for providing stress tolerance in plants
Plant Stress, 2023 Alteration of stress (abiotic and biotic) constitutes one of the major problems for normal plants health. In the present scenario, new molecular tools are broadly utilized to improve stress tolerance and high-yielding crop plants.
Monalisha Das Mohapatra +3 more
doaj +1 more source
RNA Chaperones, RNA Annealers and RNA Helicases [PDF]
RNA Biology, 2007 RNA molecules face difficulties when folding into their native structures. In the cell, proteins can assist RNAs in reaching their functionally active states by binding and stabilizing a specific structure or, in a quite opposite way, by interacting in a non-specific manner. These proteins can either facilitate RNA-RNA interactions in a reaction termed
Rajkowitsch, Lukas +9 more
openaire +3 more sources
Current Plant Biology, 2021 Helicases and translocases comprise one of the largest and highly conserved gene families in eukaryotic organisms, including plant. Members of this gene family are involved in a plethora of molecular processes related to DNA and RNA metabolism that are ...
Asif Ahmed Sami +3 more
doaj +1 more source
RNA helicases in splicing [PDF]
RNA Biology, 2013 In eukaryotic cells, introns are spliced from pre-mRNAs by the spliceosome. Both the composition and the structure of the spliceosome are highly dynamic, and eight DExD/H RNA helicases play essential roles in controlling conformational rearrangements. There is evidence that the various helicases are functionally and physically connected with each other
Olivier, Cordin, Jean D, Beggs
openaire +2 more sources
The RNA helicase database [PDF]
Nucleic Acids Research, 2010 RNA helicases are ubiquitous and essential enzymes that function in nearly all aspects of RNA metabolism. The RNA helicase database (www.rnahelicase.org) integrates the wealth of accumulating information on RNA helicases in a readily accessible format.
Jankowsky, Anja +2 more
openaire +2 more sources
DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense
Viruses, 2020 DEAD-box helicases are a large family of conserved RNA-binding proteins that belong to the broader group of cellular DExD/H helicases. Members of the DEAD-box helicase family have roles throughout cellular RNA metabolism from biogenesis to decay ...
Frances Taschuk, Sara Cherry
doaj +1 more source