Results 31 to 40 of about 768,185 (263)

RNA Helicase A Regulates the Replication of RNA Viruses [PDF]

open access: yesViruses, 2021
The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview
Rui-Zhu Shi, Yuan-Qing Pan, Li Xing
openaire   +3 more sources

Deciphering the role of helicases and translocases: A multifunctional gene family safeguarding plants from diverse environmental adversities

open access: yesCurrent Plant Biology, 2021
Helicases and translocases comprise one of the largest and highly conserved gene families in eukaryotic organisms, including plant. Members of this gene family are involved in a plethora of molecular processes related to DNA and RNA metabolism that are ...
Asif Ahmed Sami   +3 more
doaj   +1 more source

DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense

open access: yesViruses, 2020
DEAD-box helicases are a large family of conserved RNA-binding proteins that belong to the broader group of cellular DExD/H helicases. Members of the DEAD-box helicase family have roles throughout cellular RNA metabolism from biogenesis to decay ...
Frances Taschuk, Sara Cherry
doaj   +1 more source

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]

open access: yes, 2010
For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core   +3 more sources

Viral sensing by RNA helicases

open access: yesVirologie, 2020
A key aspect of antiviral immunity is the distinction between "self" and "non-self" components. This distinction can be established through the detection of double-stranded RNA (dsRNA), a common sign of viral infection, by cytosolic RNA helicases.
Rousseau, Claire, Meignin, Carine
openaire   +4 more sources

Cytoplasmic ribonucleoprotein complexes, RNA helicases and coronavirus infection

open access: yesFrontiers in Virology, 2022
RNA metabolism in the eukaryotic cell includes the formation of ribonucleoprotein complexes (RNPs) that, depending on their protein components, have a different function.
Li Wang   +4 more
doaj   +1 more source

Xp54 and related (DDX6-like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation [PDF]

open access: yes, 2006
The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus oocytes. In oocytes, several abundant proteins bind pre-mRNA transcripts to modulate nuclear export, RNA stability and translational ...
Weston, A, Sommerville, John
core   +1 more source

Putative SF2 helicases of the early-branching eukaryote Giardia lamblia are involved in antigenic variation and parasite differentiation into cysts

open access: yesBMC Microbiology, 2012
Background Regulation of surface antigenic variation in Giardia lamblia is controlled post-transcriptionally by an RNA-interference (RNAi) pathway that includes a Dicer-like bidentate RNase III (gDicer).
Gargantini Pablo R   +3 more
doaj   +1 more source

psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation

open access: yesNature Communications, 2021
ATP-dependent helicases remodel the spliceosome and proofread splice site recognition. A new method – Purified Spliceosome iCLIP (psiCLIP) – probes protein-RNA interactions in defined spliceosome complexes to reveal how the helicases Prp16 and Prp22 ...
Lisa M. Strittmatter   +9 more
doaj   +1 more source

Biological roles of DExH RNA helicase, RHAU [PDF]

open access: yes, 2007
In this thesis, I have described the work carried out on a single protein called RHAU, dealing with aspects of protein localization in cells, the regulation of global gene expression by different mechanisms, and cellular stress-responses.
Iwamoto, Fumiko
core   +1 more source

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