Results 11 to 20 of about 495,459 (282)
Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut
iScience, 2020 Summary: Diseases caused by mosquito-borne viruses have been on the rise for the last decades, and novel methods aiming to use laboratory-engineered mosquitoes that are incapable of carrying viruses have been developed to reduce pathogen transmission ...
Sarah Hélène Merkling +9 more
doaj +1 more source
RNA interference in marine and freshwater sponges [PDF]
, 2011 Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon +12 more
core +1 more source
Assessment of RNAi-induced silencing in banana (Musa spp.) [PDF]
, 2015 In plants, RNA- based gene silencing mediated by small RNAs functions at the transcriptional or post-transcriptional level to negatively regulate target genes, repetitive sequences, viral RNAs and/or transposon elements.
Cammue, B.P.A. +6 more
core +1 more source
RNA interference approaches for treatment of HIV-1 infection. [PDF]
, 2015 HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 replication and delay the onset of AIDS, viral mutagenesis often leads to
Bobbin, Maggie L +2 more
core +1 more source
Cell Death and Disease, 2023 Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1; also known as deleted in oral cancer or DOC1) is a tumor suppressor gene known to play functional roles in both cell cycle regulation and in the epigenetic control of embryonic stem cell ...
Roberto Stabile +16 more
doaj +1 more source
Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]
, 2013 RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif +2 more
core +3 more sources
Nature Communications, 2021 Defective viral genomes (DVGs) can interfere with virus replication and provide a potential approach to control infection. Here, Rezelj et al. use a combined experimental evolution and computational approach to identify DVG sequences that optimally ...
Veronica V. Rezelj +23 more
doaj +1 more source
Thrombosis Update, 2021 Objective: Venous thromboembolism (VTE) contributes to morbidity and mortality in women with ovarian cancer. Underlying mechanisms of venous thrombosis in ovarian cancer are not well-understood. The aim of this study was to identify the potential role of
Tomoyuki Sasano +6 more
doaj +1 more source
Characterization of a broad-based mosquito yeast interfering RNA larvicide with a conserved target site in mosquito semaphorin-1a genes [PDF]
, 2019 BACKGROUND: RNA interference (RNAi), which has facilitated functional characterization of mosquito neural development genes such as the axon guidance regulator semaphorin-1a (sema1a), could one day be applied as a new means of vector control ...
Duman-Scheel, Molly +9 more
core +1 more source