Results 91 to 100 of about 74,683 (214)

Overview of RNA interference therapeutics [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2012
Since the term RNA interference (RNAi) was coined in 1998, much knowledge about RNAi has accumulated. Presently,RNAi is known as a power tool for studying gene function as well as a potential therapeutic molecular technique for a widerange of disorders ...
Nattanan T-Thienprasert Panjaworayan
doaj  

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Antiviral RNA interference in plants: Increasing complexity and integration with other biological processes

Plant Communications
RNA interference (RNAi, also known as RNA silencing) is one of the most important plant defense responses against viral invasion. Although major components of the RNAi pathway, steps leading to viral small interfering RNA biogenesis, and viral ...
Fangfang Li, Xue Li, Siwen Zhao, Fuan Pan, Zhaolei Li, Yuming Hao, Jiachi He, Aiming Wang, Richard Kormelink, Xueping Zhou   +9 more
doaj   +1 more source

Innovation in pest management: can the past inform the future?

Pest Management Science, EarlyView.
Progress in pest management occurred incrementally, but occasionally, transformative discoveries introduced disruptive technologies. Looking ahead, generative artificial intelligence is expected to accelerate agricultural discovery by integrating vast datasets from mechanization, genetics, and chemistry.
Eric Moog, Franck E. Dayan
wiley   +1 more source

The first RNAi‐based biopesticide approved in the United States: regulatory implications for the European Union – the case of Ledprona (Calantha™)

Pest Management Science, EarlyView.
The approval of the RNA interference‐based biopesticide Ledprona (Calantha™) in the USA marks a milestone for RNA‐based crop protection. We discuss the regulatory implications for the European Union, highlighting opportunities, challenges, and the need for adapted risk assessment frameworks for RNA‐based plant protection products.
Aline Koch, Gabi Krczal
wiley   +1 more source

Early grower perceptions and likely acceptance of RNAi‐based biopesticides in Australia

Pest Management Science, EarlyView.
Individual decisions on the adoption of RNAi‐based biopesticides reflect balance of perceived risks and benefits. Adoption can be facilitated through tailored communication strategies highlighting clear scientific evidence of product efficacy. Abstract BACKGROUND Managing pest resistance while reducing reliance on conventional chemical pesticides ...
Raquel Tardin‐Coelho, Julian Clifton, Peta Ashworth   +2 more
wiley   +1 more source

Cross-Kingdom RNA Transport Based on Extracellular Vesicles Provides Innovative Tools for Plant Protection

Plants
RNA interference (RNAi) shows great potential in plant defense against pathogens through RNA-mediated sequence-specific gene silencing. Among RNAi-based plant protection strategies, spray-induced gene silencing (SIGS) is considered a more promising ...
Yujin Zhao, Yanguang Zhou, Jingyan Xu, Sen Fan, Na Zhu, Qingling Meng, Shijie Dai, Xiaofeng Yuan   +7 more
doaj   +1 more source

Oral RNAi reduces survival and grain loss in Rhyzopertha dominica, including phosphine‐resistant populations

Pest Management Science, EarlyView.
Oral delivery of dsRNA targeting essential genes reduces adult survival and grain damage in Rhyzopertha dominica, including highly phosphine‐resistant populations. These findings support RNAi as a complementary mode‐of‐action for resistance management and postharvest protection in stored‐grain systems. Abstract BACKGROUND Phosphine fumigation remains a
ZiHan Shen, Wei Chen, KangXu Wang
wiley   +1 more source

RNA interference of the ecdysone receptor gene AgEcR in a wolfberry ‐ specialized strain of Aphis gossypii Glover affects its survival and fecundity and confers resistance in transgenic goji (Lycium barbarum L.)

Pest Management Science, EarlyView.
AgEcR, an ecdysone receptor from Aphis gossypii, is an RNA interference (RNAi) target. Artificial diet screening of five double ‐ stranded RNA fragments identified dsAgEcR2 targeting the D/E junction as the most potent. Transgenic goji expressing dsAgEcR2 caused molting defects and reduced fecundity, suppressing population growth and offering a ...
Ting Yan, Ao‐Ga Li, Run‐Yao Bai, Long Hai, Shu‐Juan Chang, Ying Zhang, Ri‐Heng Wu   +6 more
wiley   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source