The kinetoplastid-specific transcription factor mtTF1 is essential for mitochondrial gene expression and maxicircle replication in Trypanosoma brucei. [PDF]
Berger BM +6 more
europepmc +1 more source
[Construction of RNA interference (RNAi) lentiviral expression vector of DEK gene and its effect on the biological behavior of liver cancer cells]. [PDF]
Li SH +5 more
europepmc +1 more source
Epigenetic control of cellular plasticity in breast cancer progression
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey +2 more
wiley +1 more source
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto +2 more
wiley +1 more source
Expression Profiles of Chitin Deacetylase Genes and Functional Characterization of Key Genes in <i>Spodoptera frugiperda</i>. [PDF]
Sun L +7 more
europepmc +1 more source
RNA activation in insects: From emerging evidence to molecular applications
Canonical RNA activation involves small RNAs interacting with promoter sequences, but there is also evidence of non‐canonical RNAa in eukaryotes. Emerging evidence suggests the presence of RNAa in insects. RNAa can be utilised as a tool for functional genomic studies in insects.
Sassan Asgari
wiley +1 more source
Research Progress on Target Gene Screening and the Precise Control Potential of <i>Diaphorina citri</i> Using RNA Interference. [PDF]
Ye L, He Z, Li X, Huang A, Zhou J, Yi L.
europepmc +1 more source
TcFur1, a furin 1 ortholog in Tribolium castaneum, is highly expressed in pupae and declines in adults. TcFur1 knockdown reduces oviposition but does not alter triacylglycerol levels or total lipase activity. TcFur1 knockdown increases circulating trehalose and decreases expression of insulin‐like peptides and the AKH receptor.
Julia Sanches‐Almeida +2 more
wiley +1 more source
<i>DSP1</i> regulates planarian (<i>Dugesia japonica</i>) neural regeneration depending on <i>CnB</i>. [PDF]
Gao L +7 more
europepmc +1 more source
Advances in Cytosolic dsRNA Sensing of Viral Infections
Activation of cytosolic dsRNA sensors by viral infection generates multiple outcomes. dsRNA generated during viral infection, either of viral origin or from endogenous sources, can activate multiple cytosolic dsRNA sensors. Activation of PKR critically induces protein translation shutdown via phosphorylation of eukaryotic translation initiation factor ...
Sofia Maceratessi, Natalia G. Sampaio
wiley +1 more source

