Results 1 to 10 of about 447,964 (191)
RNA Modification in Metabolism [PDF]
MedCommEpigenetic regulation in disease development has been witnessed within this decade. RNA methylation is the predominant form of epigenetic regulation, and the most prevalent modification in RNA is N6‐methyladenosine (m6A).
Yadi Liu +4 more
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Cancer Management and Research, 2022 Zhiyuan Yang,1,2,* Siyu Zhang,1,2,* Tian Xia,1,2,* Yue Fan,1,2 Ying Shan,1,2 Kaiwen Zhang,1,2 Jiayan Xiong,1,2 Miao Gu,1,2 Bo You1,2 1Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Medical ...
Yang Z +8 more
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RNA modification mapping with JACUSA2 [PDF]
Genome Biology, 2022 Several high-throughput antibody-free methods for RNA modification detection from sequencing data have been developed. We present JACUSA2 as a versatile software solution and comprehensive analysis framework for RNA modification detection assays that are
Michael Piechotta +4 more
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RNA modification: a promising code to unravel the puzzle of autoimmune diseases and CD4+ T cell differentiation [PDF]
Frontiers in ImmunologyDynamic changes in various forms of RNA modification are critical to the functional homeostasis of the immune system and the pathophysiology of autoimmune diseases. RNA modification-related proteins play an essential role in these processes.
Hui Yu +8 more
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The RNA modification database--1998 [PDF]
Nucleic Acids Research, 1998 The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from RNA, and is maintained as an updated version of the initial printed report [Limbach,P.A., Crain,P.F. and McCloskey,J.A. (1994) Nucleic Acids Res. , 22, 2183-2196].
James McCloskey
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Translational Recoding and RNA Modifications [PDF]
, 2005 During protein synthesis, codons in mRNA are translated sequentially in frame on the ribosome following strict decoding rules. This process is usually very accurate. However, in some cases, recoding events occur at selected codons, leading to a high frequency of frameshifting or stop codon readthrough.
Olivier Namy +3 more
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Comprehensive analysis of the relationship between RNA modification writers and immune microenvironment in head and neck squamous cell carcinoma [PDF]
BMC ImmunologyObjectives Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Four types of RNA modification writers (m6A, m1A, A-I editing, and APA) are widely involved in tumorigenesis and the TME.
Wei Li +4 more
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Current insights on m6A RNA modification in acute leukemia: therapeutic targets and future prospects [PDF]
Frontiers in OncologyRNA modification is the critical mechanism for regulating post-transcriptional processes. There are more than 150 RNA modifications reported so far, among which N6-Methyladenosine is the most prevalent one.
Parminder Kaur +3 more
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RNA Modification and Its Implication in Plant Pathogenic Fungi [PDF]
The Plant Pathology Journal, 2021 Interaction of a pathogen with its host plant requires both flexibility and rapid shift in gene expression programs in response to environmental cues associated with host cells. Recently, a growing volume of data on the diversity and ubiquity of internal
Junhyun Jeon, Song Hee Lee
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RNA modifications and cancer [PDF]
RNA Biology, 2020 RNA plays essential roles in not only translating nucleic acids into proteins, but also in gene regulation, environmental interactions and many human diseases. Nature uses over 150 chemical modifications to decorate RNA and diversify its functions. With the fast-growing RNA research in the burgeoning field of 'epitranscriptome', a term describes post ...
Phensinee Haruehanroengra +4 more
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