Results 11 to 20 of about 853,838 (334)
Novel Modifications in RNA [PDF]
ACS Chemical Biology, 2011 The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs.
Kelly, Phelps +2 more
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Sabiad, 2023 Objective: Post-transcriptional modifications like m6A (N6-methyladenosine) and secondary structures like G-quadruplex (G4) are formations that play a vital role in RNA processing. Their synergy also has functional consequences.
Çağrı Güleç
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The RNA modification database [PDF]
Nucleic Acids Research, 1996 The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from all RNAs, and is maintained as an updated version of the initial printed report [Limbach,P.A., Crain,P.F. and McCloskey,J.A. (1994)Nucleic Acids Res. , 22, 2183-2196].
P F, Crain, J A, McCloskey
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No evidence for age-related differences in mitochondrial RNA quality in the female germline
Reproduction and Fertility, 2022 Mitochondrial quality is implicated as a contributor to declining fertility with aging. We investigated mitochondrial transcripts in oocytes and their associated cumulus cells from mice of different ages using RNA-seq.
Fiona Hartley +7 more
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RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
, 2013 Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Ahmed +38 more
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Role of m6A in Embryonic Stem Cell Differentiation and in Gametogenesis
Epigenomes, 2020 The rising field of RNA modifications is stimulating massive research nowadays. m6A, the most abundant mRNA modification is highly conserved during evolution.
Lior Lasman +2 more
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A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]
, 2010 Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M +2 more
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RNA Modification in Carcinogenesis and Development of Gastric Cancer
Zhongliu Fangzhi Yanjiu, 2023 The occurrence of gastric cancer is closely related to environmental, genetic, and epigenetic factors. Currently, RNA modification is a research frontier and hotspot in the field of epigenetics.
XU Jiawen, WANG Qiang, WANG Shouyu
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Detection of RNA modifications [PDF]
RNA Biology, 2010 RNA nucleotide modifications are typically of low abundance and frequently go unnoticed by standard detection methods of molecular biology and cell biology. With a burst of knowledge intruding from such diverse areas as genomics, structural biology, regulation of gene expression and immunology, it becomes increasingly clear that many exciting functions
Stefanie, Kellner +2 more
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It’s the Little Things (in Viral RNA)
mBio, 2020 Chemical modifications of viral RNA are an integral part of the viral life cycle and are present in most classes of viruses. To date, more than 170 RNA modifications have been discovered in all types of cellular RNA.
Jiří František Potužník +1 more
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