Results 11 to 20 of about 835,495 (286)
RNA Interference by Single- and Double-stranded siRNA With a DNA Extension Containing a 3′ Nuclease-resistant Mini-hairpin Structure [PDF]
, 2013 Selective gene silencing by RNA interference (RNAi) involves double-stranded small interfering RNA (ds siRNA) composed of single-stranded (ss) guide and passenger RNAs.
Ahmed +38 more
core +6 more sources
RNA Modification in Carcinogenesis and Development of Gastric Cancer
Zhongliu Fangzhi Yanjiu, 2023 The occurrence of gastric cancer is closely related to environmental, genetic, and epigenetic factors. Currently, RNA modification is a research frontier and hotspot in the field of epigenetics.
XU Jiawen, WANG Qiang, WANG Shouyu
doaj +1 more source
Sabiad, 2023 Objective: Post-transcriptional modifications like m6A (N6-methyladenosine) and secondary structures like G-quadruplex (G4) are formations that play a vital role in RNA processing. Their synergy also has functional consequences.
Çağrı Güleç
doaj +1 more source
A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]
, 2010 Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M +2 more
core +3 more sources
Role of m6A in Embryonic Stem Cell Differentiation and in Gametogenesis
Epigenomes, 2020 The rising field of RNA modifications is stimulating massive research nowadays. m6A, the most abundant mRNA modification is highly conserved during evolution.
Lior Lasman +2 more
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Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]
, 2019 Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh +7 more
core +3 more sources
It’s the Little Things (in Viral RNA)
mBio, 2020 Chemical modifications of viral RNA are an integral part of the viral life cycle and are present in most classes of viruses. To date, more than 170 RNA modifications have been discovered in all types of cellular RNA.
Jiří František Potužník +1 more
doaj +1 more source
Broad role for YBX1 in defining the small noncoding RNA composition of exosomes. [PDF]
, 2017 RNA is secreted from cells enclosed within extracellular vesicles (EVs). Defining the RNA composition of EVs is challenging due to their coisolation with contaminants, lack of knowledge of the mechanisms of RNA sorting into EVs, and limitations of ...
Lambowitz, Alan M +6 more
core +1 more source
Epigenetics, 2020 The epitranscriptomic writer Alkylation Repair Homolog 8 (ALKBH8) is a transfer RNA (tRNA) methyltransferase that modifies the wobble uridine of selenocysteine tRNA to promote the specialized translation of selenoproteins.
Andrea Leonardi +12 more
doaj +1 more source
Broad application of a simple and affordable protocol for isolating plant RNA [PDF]
, 2015 BACKGROUND: Standard molecular biological methods involve the analysis of gene expression in living organisms under diverse environmental and developmental conditions. One of the most direct approaches to quantify gene expression is the isolation of RNA.
Ana Arruabarrena +8 more
core +1 more source