Results 1 to 10 of about 938,396 (235)

Retroviral RNA Processing [PDF]

Viruses, 2022
This review is an accompaniment to a Special Issue on “Retroviral RNA Processing”. It discusses post-transcriptional regulation of retroviruses, ranging from the ancient foamy viruses to more modern viruses, such as HIV-1, HTLV-1, Rous sarcoma virus ...
Karen L. Beemon
doaj   +4 more sources

Highly efficient RNA-synthesizing system that uses isolated human mitochondria: new initiation events and in vivo-like processing patterns. [PDF]

, 1984
A highly efficient RNA-synthesizing system with isolated HeLa cell mitochondria has been developed and characterized regarding its requirements and its products.
George L. Gaines, Giuseppe Attardi
openalex   +3 more sources

Characterization of RNA Processing Genes in Colon Cancer for Predicting Clinical Outcomes [PDF]

Biomarker Insights
Objective: Colon cancer is associated with multiple levels of molecular heterogeneity. RNA processing converts primary transcriptional RNA to mature RNA, which drives tumourigenesis and its maintenance.
Jianwen Hu, Yingze Ning, Yongchen Ma, Lie Sun, Guowei Chen   +4 more
doaj   +2 more sources

Neuronal RNA processing: cross-talk between transcriptional regulation and RNA-binding proteins [PDF]

Frontiers in Molecular Neuroscience
In the nervous system, alternative RNA processing is particularly prevalent, which results in the expression of thousands of transcript variants found in no other tissue.
Hasan Can Ozbulut, Hasan Can Ozbulut, Hasan Can Ozbulut, Valérie Hilgers   +3 more
doaj   +2 more sources

RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]

RNA Biology
Transcription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand, Christophe Dez, Lise Dauban, Sophie Queille, Sarah Danché, Sarra Abderrahmane, Frederic Beckouet, Olivier Gadal   +7 more
doaj   +2 more sources

Cytoplasmic mRNA recapping has limited impact on proteome complexity [PDF]

Open Biology, 2020
The m7G cap marks the 5′ end of all eukaryotic mRNAs, but there are also capped ends that map downstream within spliced exons. A portion of the mRNA transcriptome undergoes a cyclical process of decapping and recapping, termed cap homeostasis, which ...
Bernice A. Agana, Vicki H. Wysocki, Daniel R. Schoenberg   +2 more
doaj   +1 more source

HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency

Frontiers in Cellular and Infection Microbiology, 2022
HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of resting memory CD4+ T cells bearing replication-competent provirus.
Raquel Crespo, Shringar Rao, Tokameh Mahmoudi, Tokameh Mahmoudi, Tokameh Mahmoudi   +4 more
doaj   +1 more source

Staufen1 unwinds the secondary structure and facilitates the translation of fatty acid binding protein 4 mRNA during adipogenesis

Adipocyte, 2021
Adipogenesis is regulated by genetic interactions, in which post-transcriptional regulation plays an important role. Staufen double-stranded RNA binding protein 1 (Staufen1 or STAU1) plays diverse roles in RNA processing and adipogenesis.
Xiaodi Liang, Yi Jiao, Xueli Gong, Hao Gu, Nuerbiye Nuermaimaiti, Xuanyu Meng, Dihui Liu, Yaqun Guan   +7 more
doaj   +1 more source

MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer [PDF]

Open Biology, 2013
The ribonuclease III enzymes Drosha and Dicer are renowned for their central roles in the biogenesis of microRNAs (miRNAs). For many years, this has overshadowed the true versatility and importance of these enzymes in the processing of other RNA ...
Timothy M. Johanson, Andrew M. Lew, Mark M. W. Chong   +2 more
doaj   +1 more source

Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia

Biology Open, 2022
Mature transfer (t)RNAs are generated by multiple RNA processing events, which can include the excision of intervening sequences. The tRNA splicing endonuclease (TSEN) complex is responsible for cleaving these intron-containing pre-tRNA transcripts.
Casey A. Schmidt, Lucy Y. Min, Michelle H. McVay, Joseph D. Giusto, John C. Brown, Harmony R. Salzler, A. Gregory Matera   +6 more
doaj   +1 more source