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Retroviral RNA Processing

open access: yesViruses, 2022
This review is an accompaniment to a Special Issue on “Retroviral RNA Processing”. It discusses post-transcriptional regulation of retroviruses, ranging from the ancient foamy viruses to more modern viruses, such as HIV-1, HTLV-1, Rous sarcoma virus ...
Karen L. Beemon
doaj   +2 more sources

The Crosstalk Between Epigenetic Mechanisms and Alternative RNA Processing Regulation

open access: yesFrontiers in Genetics, 2020
As a co-transcriptional process, RNA processing, including alternative splicing and alternative polyadenylation, is crucial for the generation of multiple mRNA isoforms.
Jian Zhang   +6 more
doaj   +2 more sources

Fast Processing RNA-Seq on Multicore Processor

open access: goldمجلة بغداد للعلوم, 2021
RNA Sequencing (RNA-Seq) is the sequencing and analysis of transcriptomes. The main purpose of RNA-Seq analysis is to find out the presence and quantity of RNA in an experimental sample under a specific condition.
Lee Jia Bin   +3 more
doaj   +3 more sources

Parvovirus RNA Processing: Compact Genomic Organization and Unique Alternative mRNA Processing Mechanisms [PDF]

open access: yesViruses
Parvoviruses have compact genomic organizations with overlapping open reading frames and thus utilize alternative RNA processing strategies, alternative splicing, alternative polyadenylation, and alternative translation mechanisms to generate a range of ...
Lisa K. Uhl, Olufemi O. Fasina
doaj   +2 more sources

High-throughput detection of RNA processing in bacteria

open access: yesBMC Genomics, 2018
Background Understanding the RNA processing of an organism’s transcriptome is an essential but challenging step in understanding its biology. Here we investigate with unprecedented detail the transcriptome of Pseudomonas aeruginosa PAO1, a medically ...
Erin E. Gill   +12 more
doaj   +2 more sources

Characterization of RNA Processing Genes in Colon Cancer for Predicting Clinical Outcomes [PDF]

open access: yesBiomarker Insights
Objective: Colon cancer is associated with multiple levels of molecular heterogeneity. RNA processing converts primary transcriptional RNA to mature RNA, which drives tumourigenesis and its maintenance.
Jianwen Hu   +4 more
doaj   +2 more sources

Neuronal RNA processing: cross-talk between transcriptional regulation and RNA-binding proteins [PDF]

open access: yesFrontiers in Molecular Neuroscience
In the nervous system, alternative RNA processing is particularly prevalent, which results in the expression of thousands of transcript variants found in no other tissue.
Hasan Can Ozbulut   +3 more
doaj   +2 more sources

HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of resting memory CD4+ T cells bearing replication-competent provirus.
Raquel Crespo   +4 more
doaj   +1 more source

CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures [PDF]

open access: yesOpen Biology, 2020
Eukaryotic messenger RNA (mRNA) is modified by the addition of an inverted guanosine cap to the 5′ triphosphate. The cap guanosine and initial transcribed nucleotides are further methylated by a series of cap methyltransferases to generate the mature cap
Alison Galloway   +5 more
doaj   +1 more source

Surveillance-ready transcription: nuclear RNA decay as a default fate [PDF]

open access: yesOpen Biology, 2018
Eukaryotic cells synthesize enormous quantities of RNA from diverse classes, most of which are subject to extensive processing. These processes are inherently error-prone, and cells have evolved robust quality control mechanisms to selectively remove ...
Stefan Bresson, David Tollervey
doaj   +1 more source

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