Highly efficient RNA-synthesizing system that uses isolated human mitochondria: new initiation events and in vivo-like processing patterns [PDF]
, 1984 A highly efficient RNA-synthesizing system with isolated HeLa cell mitochondria has been developed and characterized regarding its requirements and its products.
Attardi, Giuseppe, Gaines, George
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Parvovirus RNA Processing: Compact Genomic Organization and Unique Alternative mRNA Processing Mechanisms [PDF]
VirusesParvoviruses have compact genomic organizations with overlapping open reading frames and thus utilize alternative RNA processing strategies, alternative splicing, alternative polyadenylation, and alternative translation mechanisms to generate a range of ...
Lisa K. Uhl, Olufemi O. Fasina
doaj +2 more sources
Characterization of RNA Processing Genes in Colon Cancer for Predicting Clinical Outcomes [PDF]
Biomarker InsightsObjective: Colon cancer is associated with multiple levels of molecular heterogeneity. RNA processing converts primary transcriptional RNA to mature RNA, which drives tumourigenesis and its maintenance.
Jianwen Hu +4 more
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Neuronal RNA processing: cross-talk between transcriptional regulation and RNA-binding proteins [PDF]
Frontiers in Molecular NeuroscienceIn the nervous system, alternative RNA processing is particularly prevalent, which results in the expression of thousands of transcript variants found in no other tissue.
Hasan Can Ozbulut +3 more
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RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability [PDF]
RNA BiologyTranscription is a major contributor to genomic instability. The ribosomal RNA (rDNA) gene locus consists of a head-to-tail repeat of the most actively transcribed genes in the genome.
Christophe Normand +7 more
doaj +2 more sources
CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures [PDF]
Open Biology, 2020 Eukaryotic messenger RNA (mRNA) is modified by the addition of an inverted guanosine cap to the 5′ triphosphate. The cap guanosine and initial transcribed nucleotides are further methylated by a series of cap methyltransferases to generate the mature cap
Alison Galloway +5 more
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HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency
Frontiers in Cellular and Infection Microbiology, 2022 HIV-1 infection remains non-curative due to the latent reservoir, primarily a small pool of resting memory CD4+ T cells bearing replication-competent provirus.
Raquel Crespo +4 more
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Adipocyte, 2021 Adipogenesis is regulated by genetic interactions, in which post-transcriptional regulation plays an important role. Staufen double-stranded RNA binding protein 1 (Staufen1 or STAU1) plays diverse roles in RNA processing and adipogenesis.
Xiaodi Liang +7 more
doaj +1 more source
MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer [PDF]
Open Biology, 2013 The ribonuclease III enzymes Drosha and Dicer are renowned for their central roles in the biogenesis of microRNAs (miRNAs). For many years, this has overshadowed the true versatility and importance of these enzymes in the processing of other RNA ...
Timothy M. Johanson +2 more
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Cytoplasmic mRNA recapping has limited impact on proteome complexity [PDF]
Open Biology, 2020 The m7G cap marks the 5′ end of all eukaryotic mRNAs, but there are also capped ends that map downstream within spliced exons. A portion of the mRNA transcriptome undergoes a cyclical process of decapping and recapping, termed cap homeostasis, which ...
Bernice A. Agana +2 more
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