Results 21 to 30 of about 955,921 (334)
RNA Processing and Export [PDF]
Messenger RNAs undergo 5' capping, splicing, 3'-end processing, and export before translation in the cytoplasm. It has become clear that these mRNA processing events are tightly coupled and have a profound effect on the fate of the resulting transcript.
Sami Hocine+2 more
openaire +3 more sources
RNA quality control is an indispensable but poorly understood process that enables organisms to distinguish functional RNAs from nonfunctional or inhibitory ones.
Amber M. Hotto+2 more
doaj +1 more source
Telomerase RNA contains a template for synthesizing telomeric DNA and has been proposed to act as a flexible scaffold for holoenzyme protein subunits in the RNP.
Evan P. Hass, David C. Zappulla
doaj +1 more source
Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases
The universal 3'-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3 ...
Kozo eTomita, Seisueke eYamashita
doaj +1 more source
Writing a wrong: Coupled RNA polymerase II transcription and RNA quality control [PDF]
Processing and maturation of precursor RNA species is coupled to RNA polymerase II transcription. Co-transcriptional RNA processing helps to ensure efficient and proper capping, splicing, and 3' end processing of different RNA species to help ensure ...
Hughes, Katlyn D.+3 more
core +1 more source
The Role of RNA and RNA Processing in Neurodegeneration: Figure 1. [PDF]
From its transcription from DNA, RNA undergoes a complex processing, including splicing and editing, and associates with specific proteins that determine its subcellular localization and stability. It is now clear that many cellular activities involve some aspects of RNA biology; in neurons,
Gallo, J M+6 more
openaire +4 more sources
Arabidopsis RanBP2-Type Zinc Finger Proteins Related to Chloroplast RNA Editing Factor OZ1
OZ1, an RNA editing factor that controls the editing of 14 cytidine targets in Arabidopsis chloroplasts, contains two RanBP2-type zinc finger (Znf) domains. The RanBP2 Znf is a C4-type member of the broader zinc finger family with unique functions and an
Andrew B. Gipson+3 more
doaj +1 more source
Ribonuclease E strongly impacts bacterial adaptation to different growth conditions
Adaptation of bacteria to changes in their environment is often accomplished by changes of the transcriptome. While we learned a lot on the impact of transcriptional regulation in bacterial adaptation over the last decades, much less is known on the role
Janek Börner+3 more
doaj +1 more source
RNA Unwinding by the Trf4/Air2/Mtr4 Polyadenylation (TRAMP) Complex [PDF]
Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p.
Anderson, James T.+3 more
core +2 more sources
FUS regulates a subset of snoRNA expression and modulates the level of rRNA modifications
FUS is a multifunctional protein involved in many aspects of RNA metabolism, including transcription, splicing, translation, miRNA processing, and replication-dependent histone gene expression.
Kishor Gawade+7 more
doaj +1 more source