Results 11 to 20 of about 778,146 (302)
, 2011 Nisu pronađeni nikakvi dokazi o postojanju precelularnog života. Svi zaključci o njegovom postojanju su pretpostavke. Iako je teško zamisliti nastanak života iz neživog, precelularni život se morao pojaviti u vrlo kratkom vremenu.
Čule, Ana-Marija
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Riboswitches and the RNA World [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Riboswitches are structured noncoding RNA domains that selectively bind metabolites and control gene expression (Mandal and Breaker 2004a; Coppins et al. 2007; Roth and Breaker 2009). Nearly all examples of the known riboswitches reside in noncoding regions of messenger RNAs where they control transcription or translation.
Ronald R. Breaker
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The RNA World: 4,000,000,050 years old [PDF]
Life, 2015 The RNA World is now some four billion years behind us, but only recently turned 50 as a human hypothesis. [...]
Niles Lehman
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In search of the RNA world on Mars. [PDF]
Geobiology, 2021 AbstractAdvances in origins of life research and prebiotic chemistry suggest that life as we know it may have emerged from an earlier RNA World. However, it has been difficult to reconcile the conditions used in laboratory experiments with real‐world geochemical environments that may have existed on the early Earth and hosted the origin(s) of life ...
Mojarro A +4 more
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RNA, 2015 My research entered the RNA world when I joined the EMBL Heidelberg. During my doctoral and postdoctoral research I had focused on developing and applying solution NMR methods and studied protein structure and dynamics of the Bcl family proteins, which are important regulators of apoptosis.
Michael Sattler
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RNA, 2013 Following the naming of the RNA World for the hypothetical biochemical world during very early life forms, the current world was named the Protein World. However, the astonishing high level of transcripts from virtually all chromosomes in an organism now found in eucaryotes, as well as their extensive roles in regulating gene expression, suggests that ...
Sidney Altman
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RNA silencing sheds light on the RNA world. [PDF]
PLoS Biology, 2006 RNA silencing — also known as RNA interference — is an intriguing phenomenon in which short, double-stranded RNA “triggers” can prevent the expression of specific genes. First discovered in plants, RNA interference is now recognized as a widespread, if not ubiquitous, phenomenon, and it is causing great excitement as an experimental technique for ...
Rachel Jones
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An Expanding World of Small RNAs [PDF]
Developmental Cell, 2014 In ciliated protozoans, small RNAs (sRNAs) are integral to guiding large-scale genomic rearrangements after mating. Sandoval et al. (2014) report in this issue of Developmental Cell the discovery of a class of Paramecium sRNAs, produced by a unique Dicer-like enzyme, that likely provides late stage quality control in this process.
Zachary T. Neeb, Alan M. Zahler
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Cold Spring Harb Perspect Biol, 2018 Although we live in the remnants of an RNA world, the world of drug discovery and chemical probes is firmly protein-centric. Developing highly selective small molecules targeting RNA is often considered to be an insurmountable challenge. Our goal is to demystify the design of such compounds.
Disney MD, Dwyer BG, Childs-Disney JL.
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Traversing the RNA world. [PDF]
J Biol Chem, 2017 An invitation to write a "Reflections" type of article creates a certain ambivalence: it is a great honor, but it also infers the end of your professional career. Before you vanish for good, your colleagues look forward to an interesting but entertaining account of the ups-and-downs of your past research and your views on science in general, peppered ...
Filipowicz W.
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