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The RNA World: Piecing together the historical development of a hypothesis
The concept of an RNA world is a hypothesis firmly rooted in empirical data and is part of a long and complex scientific perspective that goes back more than fifty years to the discovery of the central role RNA and ribonucleotides play in protein ...
Antonio Lazcano
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Transitioning to DNA genomes in an RNA world [PDF]
The unexpected ability of an RNA polymerase ribozyme to copy RNA into DNA has ramifications for understanding how DNA genomes evolved.
Razvan Cojocaru, Peter J Unrau
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The Impact of Mutant p53 in the Non-Coding RNA World [PDF]
Long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), micro RNAs (miRNAs), and extracellular RNAs (exRNAs) are new groups of RNAs with regulation activities that have low or no protein-coding ability.
Silvia Di Agostino
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News from around the RNA world: new avenues in RNA biology, biotechnology and therapeutics from the 2022 SIBBM meeting. [PDF]
Brancato V+5 more
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A novel viroid-like RNA element “Obelisks”: a major breakthrough in the RNA World [PDF]
Li Li, Xinqin Zhang, Min Wu
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Safari in the RNA world: a special issue focused on RNA biogenesis, functions, and technologies [PDF]
Chang Ya-Nan, Cheng Hong
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Editorial: The non-coding RNA world in animals and plants [PDF]
Lingling Wang+4 more
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Chaperna: linking the ancient RNA and protein worlds
As a mental framework for the transition of self-replicating biological forms, the RNA world concept stipulates a dual function of RNAs as genetic substance and catalyst.
Ahyun Son, Scott Horowitz, Baik L. Seong
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Reflections on the RNA world [PDF]
The authors of these reflections are a generation apart, yet their career paths have much in common. After training in medicine, they both followed the call of “real science” to discover a passion for the world of RNAs, a little corner of which they are now exploring jointly. This is a brief account of these meanderings.
Zavolan, Mihaela, Keller, Walter
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