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The RNA World: Piecing together the historical development of a hypothesis

open access: diamondMètode Science Studies Journal: Annual Review, 2016
The concept of an RNA world is a hypothesis firmly rooted in empirical data and is part of a long and complex scientific perspective that goes back more than fifty years to the discovery of the central role RNA and ribonucleotides play in protein ...
Antonio Lazcano
doaj   +3 more sources

Transitioning to DNA genomes in an RNA world [PDF]

open access: yeseLife, 2017
The unexpected ability of an RNA polymerase ribozyme to copy RNA into DNA has ramifications for understanding how DNA genomes evolved.
Razvan Cojocaru, Peter J Unrau
doaj   +2 more sources

The Impact of Mutant p53 in the Non-Coding RNA World [PDF]

open access: yesBiomolecules, 2020
Long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), micro RNAs (miRNAs), and extracellular RNAs (exRNAs) are new groups of RNAs with regulation activities that have low or no protein-coding ability.
Silvia Di Agostino
doaj   +2 more sources

Editorial: The non-coding RNA world in animals and plants [PDF]

open access: yesFrontiers in Genetics
Lingling Wang   +4 more
doaj   +2 more sources

Chaperna: linking the ancient RNA and protein worlds

open access: yesRNA Biology, 2021
As a mental framework for the transition of self-replicating biological forms, the RNA world concept stipulates a dual function of RNAs as genetic substance and catalyst.
Ahyun Son, Scott Horowitz, Baik L. Seong
doaj   +1 more source

Reflections on the RNA world [PDF]

open access: yesRNA, 2015
The authors of these reflections are a generation apart, yet their career paths have much in common. After training in medicine, they both followed the call of “real science” to discover a passion for the world of RNAs, a little corner of which they are now exploring jointly. This is a brief account of these meanderings.
Zavolan, Mihaela, Keller, Walter
openaire   +4 more sources

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