Results 11 to 20 of about 292,607 (304)
Assumption and Criticism on RNA World Hypothesis from Ribozymes to Functional Cells [PDF]
Bioengineering and Bioscience, 2021 The origin of life has long baffled scientists, trying to shed some light on the universe of the unknown we live in. The RNA world hypothesis is merely an idea that tries to grasp the root of life by going beyond phylogenetic trees, and the ‘Drawinian threshold'.
Sami El Khatib, Ahmad Raslan
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Casting Doubt on the RNA World Hypothesis♦ [PDF]
Journal of Biological Chemistry, 2013 openalex +3 more sources
An alternative to the RNA World Hypothesis
Trends in Evolutionary Biology, 2011 The RNA world hypothesis for the origin of life is widely accepted in spite of the complexity of RNA synthesis. An alternative hypothesis is advanced for the origin and evolution of protein and nucleic acid synthesis. At an early stage synthesis of poly-( b -malic acid), the initial evolutionary predecessor of nucleic acids, and polypeptides was ...
Brian R. Francis
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Case for an RNA–prion world: a hypothesis based on conformational diversity [PDF]
Journal of Biological Physics, 2011 Prions and other misfolded proteins can impart their structure and functions to normal molecules. Based upon a thorough structural assessment of RNA, prions and misfolded proteins, especially from the perspective of conformational diversity, we propose a case for co-existence of these in the pre-biotic world. Analyzing the evolution of physical aspects
Param Priya Singh, Anirban Banerji
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The RNA World Hypothesis: A Critical Reassessment of Prebiotic Plausibility.
Truman, Royal
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Trinity of G-tetrads and origin of translation
Biology Direct, 2022 Background The RNA world hypothesis cannot address most of the questions of the origin of life without violating the continuity principle (small Darwinian steps without foresight and miracles).
Besik Kankia
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Life, 2023 How functional peptides may have arisen is a significant problem for the scenario of the RNA world. An attractive idea, the direct RNA template (DRT) hypothesis, proposes that RNA molecules can bind amino acids specifically and promote the synthesis of ...
Yu Shi, Chunwu Yu, Wentao Ma
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The Way forward for the Origin of Life: Prions and Prion-Like Molecules First Hypothesis
Life, 2021 In this paper the hypothesis that prions and prion-like molecules could have initiated the chemical evolutionary process which led to the eventual emergence of life is reappraised.
Sohan Jheeta +3 more
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An Aminoisoxazole‐Based Proto‐RNA
ChemistryEurope, 2023 The RNA world hypothesis predicts that life started with the development of replicating and catalytically active RNA, which evolved in a process of molecular evolution to increasingly complex chemical structures.
Felix Xu +4 more
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Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]
, 2020 Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu +2 more
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