Results 21 to 30 of about 292,607 (304)

Arginine cofactors on the polymerase ribozyme. [PDF]

open access: yesPLoS ONE, 2011
The RNA world hypothesis states that the early evolution of life went through a stage in which RNA served both as genome and as catalyst. The central catalyst in an RNA world organism would have been a ribozyme that catalyzed RNA polymerization to ...
Chengguo Yao   +4 more
doaj   +1 more source

RNA Synthesis by in Vitro Selected Ribozymes for Recreating an RNA World

open access: yesLife, 2015
The RNA world hypothesis states that during an early stage of life, RNA molecules functioned as genome and as the only genome-encoded catalyst. This hypothesis is supported by several lines of evidence, one of which is the in vitro selection of catalytic
Lyssa L. Martin   +2 more
doaj   +1 more source

Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization

open access: yesNature Communications, 2021
Prebiotic compartmentalization could prove essential for the evolution of life. Guo et al. show that liquid-liquid separation in an aqueous two-phase system driven by evaporation may already suffice to facilitate chemical processes required for the RNA ...
Wei Guo   +6 more
doaj   +1 more source

The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity

open access: yesLife, 2022
The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
doaj   +1 more source

The Old and New RNA World

open access: yesActa Societatis Botanicorum Poloniae, 2014
Among the numerous hypotheses offering a scenario for the origin of life on Earth, the one called “The RNA World” has gained the most attention. According to this hypothesis RNA acted as a genetic information storage material, as a catalyst of all ...
Zofia Szweykowska-Kulińska
doaj   +1 more source

Applications of phage-derived RNA-based technologies in synthetic biology

open access: yesSynthetic and Systems Biotechnology, 2020
As the most abundant biological entities with incredible diversity, bacteriophages (also known as phages) have been recognized as an important source of molecular machines for the development of genetic-engineering tools.
Wenhui Zhang, Qiong Wu
doaj   +1 more source

The Origin of Life: Models and Data. [PDF]

open access: yes, 2017
A general framework for conventional models of the origin of life (OOL) is the specification of a 'privileged function.' A privileged function is an extant biological function that is excised from its biological context, elevated in importance over other
Lanier, Kathryn A, Williams, Loren Dean
core   +1 more source

Primordial soup or vinaigrette: did the RNA world evolve at acidic pH?

open access: yesBiology Direct, 2012
Background The RNA world concept has wide, though certainly not unanimous, support within the origin-of-life scientific community. One view is that life may have emerged as early as the Hadean Eon 4.3-3.8 billion years ago with an atmosphere of high CO2 ...
Bernhardt Harold S, Tate Warren P
doaj   +1 more source

The RNA World: 4,000,000,050 years old

open access: yesLife, 2015
The RNA World is now some four billion years behind us, but only recently turned 50 as a human hypothesis. [...]
Niles Lehman
doaj   +1 more source

Twenty years of "Lipid World": a fertile partnership with David Deamer [PDF]

open access: yes, 2019
"The Lipid World" was published in 2001, stemming from a highly effective collaboration with David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in Israel.
Kahana, Amit   +2 more
core   +1 more source

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