Results 21 to 30 of about 370,027 (271)

Trinity of G-tetrads and origin of translation

open access: yesBiology Direct, 2022
Background The RNA world hypothesis cannot address most of the questions of the origin of life without violating the continuity principle (small Darwinian steps without foresight and miracles).
Besik Kankia
doaj   +1 more source

The Way forward for the Origin of Life: Prions and Prion-Like Molecules First Hypothesis

open access: yesLife, 2021
In this paper the hypothesis that prions and prion-like molecules could have initiated the chemical evolutionary process which led to the eventual emergence of life is reappraised.
Sohan Jheeta   +3 more
doaj   +1 more source

Exploring the Lipid World Hypothesis: A Novel Scenario of Self-Sustained Darwinian Evolution of the Liposomes

open access: yesAstrobiology, 2023
According to the Lipid World hypothesis, life on Earth originated with the emergence of amphiphilic assemblies in the form of lipid micelles and vesicles (liposomes).
V. Subbotin, G. Fiksel
semanticscholar   +1 more source

RNA World Modeling: A Comparison of Two Complementary Approaches

open access: yesEntropy, 2022
Simple Summary Despite years of dedicated research, scientists are still not sure what the first ”living” cell would have looked like. One of the most well-known hypotheses is the RNA world hypothesis, which assumes that, in the beginning, life relied on
Jaroslaw Synak   +2 more
semanticscholar   +1 more source

An Aminoisoxazole‐Based Proto‐RNA

open access: yesChemistryEurope, 2023
The RNA world hypothesis predicts that life started with the development of replicating and catalytically active RNA, which evolved in a process of molecular evolution to increasingly complex chemical structures.
Felix Xu   +4 more
doaj   +1 more source

A Textual Deconstruction of the RNA World

open access: yesBiosemiotics, 2021
RNAs can do many things. They can store information, act in the world, and respond to the world. Because of these capabilities biologists have proposed a primordial ‘RNA world’ in which RNA, rather than DNA, performed the central role of replicator and ...
D. Haig
semanticscholar   +1 more source

Arginine cofactors on the polymerase ribozyme. [PDF]

open access: yesPLoS ONE, 2011
The RNA world hypothesis states that the early evolution of life went through a stage in which RNA served both as genome and as catalyst. The central catalyst in an RNA world organism would have been a ribozyme that catalyzed RNA polymerization to ...
Chengguo Yao   +4 more
doaj   +1 more source

Rewriting Human History and Empowering Indigenous Communities with Genome Editing Tools. [PDF]

open access: yes, 2020
Appropriate empirical-based evidence and detailed theoretical considerations should be used for evolutionary explanations of phenotypic variation observed in the field of human population genetics (especially Indigenous populations). Investigators within
Fox, Keolu   +2 more
core   +2 more sources

Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization

open access: yesNature Communications, 2021
Prebiotic compartmentalization could prove essential for the evolution of life. Guo et al. show that liquid-liquid separation in an aqueous two-phase system driven by evaporation may already suffice to facilitate chemical processes required for the RNA ...
Wei Guo   +6 more
doaj   +1 more source

The Effect of Environment on the Evolution and Proliferation of Protocells of Increasing Complexity

open access: yesLife, 2022
The formation, growth, division and proliferation of protocells containing RNA strands is an important step in ensuring the viability of a mixed RNA–lipid world.
Suvam Roy, Supratim Sengupta
doaj   +1 more source

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