Results 31 to 40 of about 195,676 (344)
An efficient deep learning based predictor for identifying miRNA-triggered phasiRNA loci in plant
Mathematical Biosciences and Engineering, 2023 Phasic small interfering RNAs are plant secondary small interference RNAs that typically generated by the convergence of miRNAs and polyadenylated mRNAs.
Yuanyuan Bu, Jia Zheng , Cangzhi Jia
doaj +1 more source
Exit from Pluripotency Assay of Mouse Embryonic Stem Cells
Bio-Protocol, 2017 A novel method to assess the dissolution of the core pluripotency transcription-factor circuit of mouse Embryonic Stem Cells (mESCs) has been developed (Ying et al., 2003; Betschinger et al., 2013).
Daniel Cirera-Salinas, Constance Ciaudo
doaj +1 more source
Application of Exogenous dsRNAs-induced RNAi in Agriculture: Challenges and Triumphs
Frontiers in Plant Science, 2020 In recent years, RNA interference (RNAi) machinery has widely been explored by plant biologists for its potential applications in disease management, plant development, and germplasm improvement.
P. Das, S. Sherif
semanticscholar +1 more source
European Journal of Entomology, 2017 RNA interference (RNAi) technology uses dsRNAs to silence specific targeted genes by downregulating their expression. It has become a potent tool for functional and regulatory studies of insect genes and has potential to be applied for insect control ...
Saikat Kumar B. GHOSH +1 more
doaj +1 more source
Effects of silencing APN gene on proliferation, invasion and apoptosis of human glioma U251 cells
Di-san junyi daxue xuebao, 2020 Objective To determine the effect of aminopeptidase N (APN) on the proliferation, invasion, and apoptosis in human glioma U251 cells and to investigate the possible mechanism.
DONG Yunpeng, CHENG Yuan, CHEN Jin
doaj +1 more source
RNAi: What is its position in agriculture?
Journal of Pest Science, 2020 RNA interference (RNAi) is being developed and exploited to improve plants by modifying endogenous gene expression as well as to target pest and pathogen genes both within plants (i.e.
B. Mezzetti +11 more
semanticscholar +1 more source
Current efforts in the analysis of RNAi and RNAi target genes [PDF]
Briefings in Bioinformatics, 2005 RNAi is RNA interference by short RNAs. It influences gene-expression by down-regulation of mRNAs, typically by complementarity to the 3' UTR (untranslated region) of the mRNA. microRNAs (miRNAs) are short RNAs acting as natural RNAi. miRNAs mediate down-regulation of many mRNAs from developmental genes and transcription factor genes.
Peter Bengert, Thomas Dandekar
openaire +3 more sources
Perspective: machines for RNAi [PDF]
Genes & Development, 2005 RNA silencing pathways convert the sequence information in long RNA, typically double-stranded RNA, into ∼21-nt RNA signaling molecules such as small interfering RNAs (siRNAs) and microRNAs (miRNAs). siRNAs and miRNAs provide specificity to protein effector complexes that repress mRNA transcription or translation, or catalyze mRNA destruction. Here, we
Tomari, Yukihide, Zamore, Phillip D.
openaire +4 more sources
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Nature, 2010 Therapeutics that are designed to engage RNA interference (RNAi) pathways have the potential to provide new, major ways of imparting therapy to patients.
Mark E. Davis +8 more
semanticscholar +1 more source
Comparative miRomics of Salt-Tolerant and Salt-Sensitive Rice
Journal of Integrative Bioinformatics, 2017 Increase in soil salt causes osmotic and ionic stress to plants, which inhibits their growth and productivity. Rice production is also hampered by salinity and the effect of salt is most severe at the seedling and reproductive stages. Salainity tolerance
Goswami Kavita +2 more
doaj +1 more source