Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]
, 2013 RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif +2 more
core +3 more sources
European Journal of Entomology, 2017 RNA interference (RNAi) technology uses dsRNAs to silence specific targeted genes by downregulating their expression. It has become a potent tool for functional and regulatory studies of insect genes and has potential to be applied for insect control ...
Saikat Kumar B. GHOSH +1 more
doaj +1 more source
An efficient deep learning based predictor for identifying miRNA-triggered phasiRNA loci in plant
Mathematical Biosciences and Engineering, 2023 Phasic small interfering RNAs are plant secondary small interference RNAs that typically generated by the convergence of miRNAs and polyadenylated mRNAs.
Yuanyuan Bu, Jia Zheng , Cangzhi Jia
doaj +1 more source
GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics
Nucleic Acid Therapeutics, 2018 Short-interfering RNA (siRNA)-induced RNAi responses have great potential to treat a wide variety of human diseases from cancer to pandemic viral outbreaks to Parkinson's Disease.
Aaron D. Springer, S. Dowdy
semanticscholar +1 more source
Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. [PDF]
, 2015 The production of offspring is energetically costly and relies on incompletely understood mechanisms that generate a positive energy balance. In mothers of many species, changes in key energy-associated internal organs are common yet poorly characterised
Abdou +90 more
core +2 more sources
RNAi: What is its position in agriculture?
Journal of Pest Science, 2020 RNA interference (RNAi) is being developed and exploited to improve plants by modifying endogenous gene expression as well as to target pest and pathogen genes both within plants (i.e.
B. Mezzetti +11 more
semanticscholar +1 more source
Comparative miRomics of Salt-Tolerant and Salt-Sensitive Rice
Journal of Integrative Bioinformatics, 2017 Increase in soil salt causes osmotic and ionic stress to plants, which inhibits their growth and productivity. Rice production is also hampered by salinity and the effect of salt is most severe at the seedling and reproductive stages. Salainity tolerance
Goswami Kavita +2 more
doaj +1 more source
Targeted mutagenesis of the Sap47 gene of Drosophila: Flies lacking the synapse associated protein of 47 kDa are viable and fertile [PDF]
, 2004 BACKGROUND: Conserved proteins preferentially expressed in synaptic terminals of the nervous system are likely to play a significant role in brain function.
Becker, Sonja +4 more
core +3 more sources
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Nature, 2010 Therapeutics that are designed to engage RNA interference (RNAi) pathways have the potential to provide new, major ways of imparting therapy to patients.
Mark E. Davis +8 more
semanticscholar +1 more source
Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance [PDF]
, 2013 Alfredo Ghezzi, Harish R. Krishnan, Linda Lew, Francisco J. Prado III, Darryl S. Ong, Nigel S. Atkinson, Section of Neurobiology and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas, United States of ...
Atkinson, Nigel S. +5 more
core +12 more sources