Results 121 to 130 of about 2,413,680 (306)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
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, 2006 Includes bibliographical references (leaves 74-87).Absenteeism in the nursing profession poses a serious threat to South African health care institutions (Samdi, 2000; McHugh, 2001). This research investigated the association between role stress, and the
Behrman, Melanie
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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The Role of Organizational Commitment in Occupational Stress Models
, 2008 This study examined affective organizational commitment (AOC) and con- tinuance organizational commitment (COC) as moderators of the relation- ship between job-related anxiety and intention to leave among 506 Israeli nurses who completed self ...
Glazer, Sharon, Kruse, Bradford
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
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, 2020 In the postmenopausal period, women undergo physical and morphological changes that may result in insufficiency and deterioration in physiological functions. It is accepted that oxidative stress is involved in the etiology of postmenopausal changes.
Yener YAZĞAN +3 more
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Nursing Teachers’ Perception of Role Strain: A Qualitative Study
Journal of Research Development in Nursing and Midwifery, 2015 Background and Objective: Role Strain refers to the felt difficulty in fulfilling expectations, complying with the role obligations and balancing the various dimensions of roles. Role strain is a subjective state of distress experienced.
Shohreh Kolagari +4 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Job-related stress and burnout
, 2002 Occupational stress is a topic of substantial interest to organizational researchers and managers, as well as society at large. Stress arising from work conditions can be pervasive and significant in its impact on individuals, their families and ...
Cooper, Cary L. +1 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
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