Results 121 to 130 of about 37,245 (219)

The SOS response of Listeria monocytogenes is involved in stress resistance and mutagenesis [PDF]

The SOS response is a conserved pathway that is activated under certain stress conditions and is regulated by the repressor LexA and the activator RecA.
Abee, T., Molenaar, D., Schalkwijk, S., van, Veen, S., van der, Vos, W.M., de, Wells-Bennik, M.H.J.   +5 more
core   +1 more source

Salmonella typhimurium rpoB and rpoC genes cloned on λ phages

FEBS Letters, 1985
Salmonella typhimurium rpoB and rpoC genes, coding for the RNA polymerase subunits β and β', respectively, were isolated on λ phages. Like their E. coli counterparts the two genes are closely linked and probably share a common promoter. The distribution of the target sites for several restriction enzymes, however, shows considerable divergence from ...
openaire   +2 more sources

吉林省耐多药结核分枝杆菌rpoB及katG基因突变特征分析

Zhongguo shiyan zhenduanxue, 2017
目的分析吉林省耐多药结核分枝杆菌临床分离株rpoB、katG基因突变特点,为建立本省快速耐多药检测方法提供参考。方法对吉林省耐多药结核分枝杆菌菌株扩增rpoB、katG基因测序后比对分析。结果耐多药结核分枝杆菌rpoB、katG基因的突变率分别为83.53%和70.6%,突变类型包括点突变、联合突变和缺失。在rpoB基因中,82.30%突变发生在RRDR区域,最常见突变位点为rpoB 531、rpoB 526、rpoB 516。KatG基因突变率为70.6%,最常见突变位点为katG315 ...
张炜煜, 杨修军, 王慧, 张立夫, 李可维   +4 more
doaj  

Molecular Study of the (rpoB) Gene as a Diagnostic Tool in Acinetobacter baumannii and the Identification of the Mutations in this Gene Led to Rifampicin Resistance

Medical Journal of Babylon
Background: Rifampicins are bactericidal antibiotics that prevent the synthesis of RNA by interacting with the rpoB-gene encoded bacterial RNA polymerase beta subunit.
Safaa Hadi Hussein, Mayaada Salall Mahdi
doaj   +1 more source

Identification of echinoderm metabolites as potential inhibitors targeting wild-type and mutant forms of Escherichia coli RNA polymerase (RpoB) for tuberculosis treatment.

PLoS ONE
Tuberculosis (TB) remains a critical global health challenge, with the emergence of drug-resistant strains heightening concerns. The development of effective drugs targeting both wild-type (WT) and mutant Escherichia coli RNA polymerase β subunit (RpoB ...
Fatimah M Alsulais, Bayan A Alhaidhal, Ramzi A Mothana, Abdullah R Alanzi   +3 more
doaj   +1 more source

Genetic diversity of Bartonella rpoB haplotypes in domestic cats from Chile

Comparative Immunology, Microbiology and Infectious Diseases
The study aimed to determine the inter and intra-host Bartonella spp. genetic diversity in cats from Chile. 'Seventy-nine cats' blood DNA samples qPCR Bartonella spp. positive were subjected to T-A cloning of Bartonella spp. rpoB partial gene (825 bp), and sequencing by Sanger method.
Sepúlveda-García, Paulina, Jara, Ronald, Mella, Armin, Monti, Gustavo, Canales, Nivia, Furquim, Maria Eduarda Chiaradia, André, Marcos Rogério, Müller, Ananda   +7 more
openaire   +2 more sources

Global prevalence of Mycobacterium massiliense strains with recombinant rpoB genes (Rec-Mas) horizontally transferred from Mycobacterium abscessus: two major types, dominant circulating clone 7 and MLST ST46 sequence type

Microbiology Spectrum
Mycobacterium abscessus is a group of emerging antimicrobial-resistant nontuberculous mycobacteria that causes severe lung disease in infected patients globally.
Dong Hyun Kim, Hyejun Seo, Sangkwon Jung, Bum-Joon Kim   +3 more
doaj   +1 more source

Desain Primer Secara in Silico Untuk Amplifikasi Fragmen Gen Rpob Mycobacterium Tuberculosis Dengan Polymerase Chain Reaction (Pcr) [PDF]

, 2013
Amplifikasi DNA Mycobacterium tuberculosis dari gen rpoB dilakukan dengan metode polymerase chain reaction (PCR). Amplifikasi DNA dengan PCR diperlukan sepasang primer (forward dan reverse) untuk membatasi daerah yang ingin diamplifikasi.
C, Y. S. (Yowani), G, P. D. (Pradnyaniti), N, W. I. (Wirajana)   +2 more
core  

Characterization of rpoB Gene mutations in Mycobacterium tuberculosis

Indian Journal of Medical Microbiology, 2021
Pratik Thosani, Santosh Karade, Ashwini Agarwal, S.P.S. Shergill, C.D.S. Katoch, Rajiv Mohan Gupta   +5 more
openaire   +1 more source

Molecular characterization of rifabutin-resistance in refractory Helicobacter pylori infection in Taiwan

International Journal of Infectious Diseases
Objectives: To explore the molecular characteristics of rpoB, encoding β-subunit of DNA-directed RNA polymerase, and unravel the link to rifabutin-resistance in patients with refractory Helicobacter pylori infection. Methods: From January 2018-March 2021,
Chia-Jung Kuo, Ngoc-Niem Bui, Jun-Nong Ke, Cheng-Yu Lin, Wey-Ran Lin, Ming-Ling Chang, Hui-Yu Wu, Mei-Zi Huang, Cheng-Hsun Chiu, Cheng-Tang Chiu, Chih-Ho Lai   +10 more
doaj   +1 more source