Results 41 to 50 of about 37,245 (219)

Mutations in rpoB and katG genes of multidrug resistant mycobacterium tuberculosis undetectable using genotyping diagnostic methods

open access: yesThe Pan African Medical Journal, 2017
INTRODUCTION: Tuberculosis remains the leading causes of death worldwide with frequencies of mutations in rifampicin and isoniazid resistant Mycobacterium tuberculosis isolates varying according to geographical location.
Faustinos Tatenda Takawira   +4 more
doaj   +1 more source

Rifampicin-resistance, rpoB polymorphism and RNA polymerase genetic engineering

open access: yesJournal of Biotechnology, 2015
Following its introduction in 1967, rifampicin has become a mainstay of therapy in the treatment of tuberculosis, leprosy and many other widespread diseases. Its potent antibacterial activity is due to specific inhibition of bacterial RNA polymerase. However, resistance to rifampicin was reported shortly after its introduction in the medical practice ...
ALIFANO, Pietro   +3 more
openaire   +3 more sources

Candidatus Bartonella merieuxii, a potential new zoonotic Bartonella species in canids from Iraq. [PDF]

open access: yes, 2012
Bartonellae are emerging vector-borne pathogens infecting erythrocytes and endothelial cells of various domestic and wild mammals. Blood samples were collected from domestic and wild canids in Iraq under the United States Army zoonotic disease ...
Breitschwerdt, Edward B   +7 more
core   +2 more sources

The mutation rate of rpoB gene showed an upward trend with the increase of MIRU10, MIRU39 and QUB4156 repetitive number

open access: yesBMC Genomics, 2023
Background Mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) is a frequently used typing method for identifying the Beijing genotype of Mycobacterium tuberculosis (Mtb), which is easily transformed into rifampicin (RIF)
Fan Su   +9 more
doaj   +1 more source

Circulation of Highly Drug-Resistant Clostridium difficile Ribotypes 027 and 001 in Two Tertiary-Care Hospitals in Mexico [PDF]

open access: yes, 2018
© 2018, Mary Ann Liebert, Inc.OBJECTIVE: To assess drug susceptibility and characterize Clostridium difficile ribotypes in isolates from two tertiary-care hospitals in Mexico.
Adrian Martinez-Melendez, Adrian   +10 more
core   +2 more sources

Sequence and analysis of the rpoB gene of Mycobacterium smegmatis [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1995
The rpoB gene encodes the beta subunit of the DNA-dependent RNA polymerase of bacteria. Mutations in defined areas result in resistance to rifampin. Mycobacterium smegmatis is naturally resistant to rifampin, but analysis of the rpoB gene revealed no identifiable rifampin resistance mutations. Another mechanism of resistance may be present.
S V, Hetherington   +2 more
openaire   +2 more sources

Rarity of rpoB Mutations Outside the Rifampicin Resistance-Determining Region of Mycobacterium tuberculosis Isolates from Patients Responding Poorly to First-Line Tuberculosis Regimens in Beijing, China: A Retrospective Study

open access: yesInfection and Drug Resistance, 2021
Jidong Guo,1,* Rongmei Liu,1,* Jin Shi,1,* Fengmin Huo,2 Yuanyuan Shang,3 Fen Wang,2 Mengqiu Gao,1 Shanshan Li3 1Department of Tuberculosis, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis & Thoracic Tumor Research ...
Guo J   +7 more
doaj  

Regulation of plasmid-encoded isoprene metabolism in Rhodococcus, a representative of an important link in the global isoprene cycle [PDF]

open access: yes, 2015
Emissions of biogenic volatile organic compounds (VOCs) form an important part of the global carbon cycle, comprising a significant proportion of net ecosystem productivity.
Crombie, Andrew T.   +7 more
core   +1 more source

Molecular evidence of lateral gene transfer in rpoB gene of Mycobacterium yongonense strains via multilocus sequence analysis. [PDF]

open access: yesPLoS ONE, 2013
Recently, a novel species, Mycobacterium yongonense (DSM 45126(T)), was introduced and while it is phylogenetically related to Mycobacterium intracellulare, it has a distinct RNA polymerase β-subunit gene (rpoB) sequence that is identical to that of ...
Byoung-Jun Kim   +3 more
doaj   +1 more source

Novel Corynebacterium diphtheriae in domestic cats [PDF]

open access: yes, 2010
Novel nontoxigenic Corynebacterium diphtheriae was isolated from a domestic cat with severe otitis. Contact investigation and carrier study of human and animal contacts yielded 3 additional, identical isolates from cats, although no evidence of zoonotic ...
Hall, Aron J.   +14 more
core   +1 more source

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