ESNOQ, proteomic quantification of endogenous S-nitrosation. [PDF]
PLoS ONE, 2010 S-nitrosation is a post-translational protein modification and is one of the most important mechanisms of NO signaling. Endogenous S-nitrosothiol (SNO) quantification is a challenge for detailed functional studies.
Xixi Zhou +6 more
doaj +4 more sources
A Fluorescent Probe for Imaging and Treating S-Nitrosation Stress in OGD/R Cells [PDF]
AntioxidantsProtein S-nitrosation, a redox post-translational modification elicited by nitric oxide (NO), is essential for modulating diverse protein functions and signaling pathways.
Hui Ye +8 more
doaj +2 more sources
Human Cystathionine γ-Lyase Is Inhibited by s-Nitrosation: A New Crosstalk Mechanism between NO and H2S [PDF]
Antioxidants, 2021 The ‘gasotransmitters’ hydrogen sulfide (H2S), nitric oxide (NO), and carbon monoxide (CO) act as second messengers in human physiology, mediating signal transduction via interaction with or chemical modification of protein targets, thereby regulating ...
Dalila G. F. Fernandes +7 more
doaj +2 more sources
In Vivo Studies on the Interaction Between Orally Administered Nitrite and Omeprazole: Beyond Proton-Catalyzed S-Nitrosation [PDF]
AntioxidantsInorganic nitrite contributes to the nitrosation of biomolecules and exerts antioxidant effects. The proton pump inhibitor omeprazole has pro-oxidant effects, inhibits the formation of nitroso species in the stomach, and abrogates the blood pressure ...
Macario A. Rebelo +11 more
doaj +2 more sources
Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer [PDF]
Redox Biology, 2020 Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies.
Raúl González +14 more
doaj +2 more sources
From S-nitrosation targets to drugs: A potential new paradigm in disease treatment [PDF]
Acta Pharmaceutica Sinica BHui Ye +5 more
doaj +2 more sources
S-nitrosation and neuronal plasticity. [PDF]
Br J Pharmacol, 2015 Nitric oxide (NO) has long been recognized as a multifaceted participant in brain physiology. Despite the knowledge that was gathered over many years regarding the contribution of NO to neuronal plasticity, for example the ability of the brain to change in response to new stimuli, only in recent years have we begun to understand how NO acts on the ...
Santos AI, Martínez-Ruiz A, Araújo IM.
europepmc +6 more sources
Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia [PDF]
Autophagy, 2017 Tao Xu, Yuying Zhang, Lei Wang
exaly +2 more sources
Oxygen-linked S-nitrosation in fish myoglobins: a cysteine-specific tertiary allosteric effect. [PDF]
PLoS ONE, 2014 The discovery that cysteine (Cys) S-nitrosation of trout myoglobin (Mb) increases heme O2 affinity has revealed a novel allosteric effect that may promote hypoxia-induced nitric oxide (NO) delivery in the trout heart and improve myocardial efficiency. To
Signe Helbo +5 more
doaj +1 more source
Chemical methods to detect S-nitrosation [PDF]
Current Opinion in Chemical Biology, 2011 Nitric oxide (NO) is a cell-signaling molecule involved in a number of physiological and pathophysiological processes. Modification of cysteine residues by NO (or NO metabolites), that is S-nitrosation, changes the function of a broad spectrum of proteins.
Wang, Hua, Xian, Ming
openaire +3 more sources