Pharmacological Inhibition of S-Nitrosoglutathione Reductase Reduces Cardiac Damage Induced by Ischemia–Reperfusion [PDF]
Antioxidants, 2021 The cardioprotective effects of nitric oxide (NO) have been described through S-nitrosylation of several important proteins in the mitochondria of the cardiomyocyte.
Oscar Arriagada Castillo +4 more
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Novel and conserved functions of S-nitrosoglutathione reductase in tomato [PDF]
Journal of Experimental Botany, 2019 Novel functions of GSNOR have been uncovered in tomato.
Adil Hussain +5 more
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Quantitative Proteome Profiling of a S-Nitrosoglutathione Reductase (GSNOR) Null Mutant Reveals a New Class of Enzymes Involved in Nitric Oxide Homeostasis in Plants [PDF]
Frontiers in Plant Science, 2021 Nitric oxide (NO) is a short-lived radical gas that acts as a signaling molecule in all higher organisms, and that is involved in multiple plant processes, including germination, root growth, and fertility.
Patrick Treffon +5 more
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S-nitrosoglutathione reductase alleviates morphine analgesic tolerance by restricting PKCα S-nitrosation [PDF]
Redox BiologyMorphine, a typical opiate, is widely used for controlling pain but can lead to various side effects with long-term use, including addiction, analgesic tolerance, and hyperalgesia.
Ling-Yan Su +10 more
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S-Nitrosoglutathione Reductase Contributes to Thermotolerance by Modulating High Temperature-Induced Apoplastic H2O2 in Solanum lycopersicum [PDF]
Frontiers in Plant Science, 2022 S-nitrosoglutathione reductase (GSNOR) is considered as a critical regulator of plant stress tolerance for its impacts on protein S-nitrosylation through regulation of the S-nitrosothiol (SNO) level.
Xuewei Song +5 more
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Tomato Root Growth Inhibition by Salinity and Cadmium Is Mediated By S-Nitrosative Modifications of ROS Metabolic Enzymes Controlled by S-Nitrosoglutathione Reductase [PDF]
Biomolecules, 2019 S-nitrosoglutathione reductase (GSNOR) exerts crucial roles in the homeostasis of nitric oxide (NO) and reactive nitrogen species (RNS) in plant cells through indirect control of S-nitrosation, an important protein post-translational modification in ...
Tereza Jedelská +5 more
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Pathophysiological Role of S-Nitrosylation and Transnitrosylation Depending on S-Nitrosoglutathione Levels Regulated by S-Nitrosoglutathione Reductase [PDF]
Biomolecules & Therapeutics, 2018 Nitric oxide (NO) mediates various physiological and pathological processes, including cell proliferation, differentiation, and inflammation. Protein S-nitrosylation (SNO), a NO-mediated reversible protein modification, leads to changes in the activity and function of target proteins.
Choi MS.
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S-nitrosoglutathione reductase inhibition regulates allergen-induced lung inflammation and airway hyperreactivity. [PDF]
PLoS ONE, 2013 Allergic asthma is characterized by Th2 type inflammation, leading to airway hyperresponsivenes, mucus hypersecretion and tissue remodeling. S-Nitrosoglutathione reductase (GSNOR) is an alcohol dehydrogenase involved in the regulation of intracellular ...
Maria E Ferrini +5 more
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The Physiological Implications of S-Nitrosoglutathione Reductase (GSNOR) Activity Mediating NO Signalling in Plant Root Structures [PDF]
Antioxidants, 2020 Nitrogen remains an important macronutrient in plant root growth due to its application in amino acid production, in addition to its more elusive role in cellular signalling through nitric oxide (NO).
Leslie Ventimiglia, Bulent Mutus
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Exogenous Nitric Oxide Enhances Disease Resistance by Nitrosylation and Inhibition of S-Nitrosoglutathione Reductase in Peach Fruit [PDF]
Frontiers in Plant Science, 2020 Nitric oxide (NO), a signaling molecule, participates in defense responses during plant–pathogen interactions. S-Nitrosoglutathione (GSNO) is found to be an active intracellular NO storage center and regulated by S-nitrosoglutathione reductase (GSNOR) in
Zifei Yu +5 more
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