Stability analysis of sodium saccharin in fried nuts and seeds—Determination of sodium saccharin and o-sulfamoylbenzoic acid by HPLC [PDF]
Frontiers in NutritionSince the invention of synthetic sweeteners, there has been considerable debate regarding the safety of some of these sweeteners due to their poor thermal stability.
Li Mu +7 more
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No Evidence of Metabolomic Disruptions From Real‐World Intakes of Aspartame or Saccharin: The Coronary Artery Risk Development in Young Adults Study [PDF]
Journal of DiabetesBackground Artificial sweeteners have become ubiquitous additives in the food supply, and yet the safety of their regular consumption remains controversial.
Brian T. Steffen +8 more
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AgRP neuron activity enhances reward-related consummatory behaviors during energy deficit in mice [PDF]
Communications BiologyHunger enhances the consumption of rewarding foods, but the neurobiological basis of this adaptation remains unclear. We hypothesize that agouti-related protein (AgRP) neurons in the hypothalamic arcuate nucleus (ARH) promote the consumption of rewarding
Daniela A. Cassano +12 more
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Scalable and sustainable reductive amidation of nitroarenes, nitroalkenes, and nitroalkyls with acyl saccharins in aqueous media [PDF]
Communications ChemistryAmide bond formation is essential in both organic and medicinal chemistry, however, most existing methods present poor ecological efficiency. Here, we report a scalable and sustainable method for synthesizing N-substituted amides from nitroarenes ...
Sunil L. Khamkar +6 more
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Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics [PDF]
EMBO Molecular MedicineSaccharin has been part of the human diet for over 100 years, and there is a comprehensive body of evidence demonstrating that it can influence the gut microbiome, ultimately impacting human health. However, the precise mechanisms through which saccharin
Rubén de Dios +16 more
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Determination of saccharin in pharmaceuticals by high performance thin layer chromatography [PDF]
Journal of the Serbian Chemical Society, 2006 A simple, accurate and selective high performance thin layer chromatographic method for the determination of saccharin in pharmaceuticals has been developed.
Čakar Mira, Popović Gordana
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Frontiers in Psychiatry, 2023 IntroductionUnderstanding the modulations of the medial prefrontal cortex (mPFC) in the valence of the stimulus from rewarding and aversive status to neutral status is crucial for the development of novel treatments for drug addiction.
Ying Hao Yu +8 more
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Diabetes Care, 1989 Saccharin, a nonnutritive sweetener discovered in 1879, has been the subject of controversy concerning its effect on public health on several occasions during this century. Over this period, the substance has come to be regarded as a useful commodity in the dietary management of diabetes mellitus.
S A, Miller, V P, Frattali
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Nematicidal Activities of Saccharin and Erythritol Against Pinewood Nematode
Journal of Nematology, 2022 The pinewood nematode (PWN), Bursaphelenchus xylophilus (Steiner & Bührer), causes pine wilt disease (PWD) resulting in severe environmental damage to pine forest ecosystems worldwide.
Kim Junheon, Lee Sujin
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The effects of saccharin on the electrodeposition of NiCoFe films on a flexible substrate
Materials Research Express, 2021 In this work, the influence of saccharin on the electrodeposition of NiCoFe film on a flexible substrate was investigated. NiCoFe electrodeposition was carried out at different potentials from electrolytes both with and without saccharin. The addition of
Setia Budi, Azwar Manaf
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