Results 181 to 190 of about 65,186 (354)
MYOCARDIAL ULTRASTRUCTURE IN LAMBS: COMPARISON OF SARCOMERE LENGTH AND INTRACELLULAR ORGANIZATION [PDF]
, 1977 Thomas A. Riemenschneider +3 more
openalex +1 more source
Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors
Medicinal Research Reviews, EarlyView.ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara +3 more
wiley +1 more source
Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies
eLifeThe giant striated muscle protein titin integrates into the developing sarcomere to form a stable myofilament system that is extended as myocytes fuse.
Judith Hüttemeister +9 more
doaj +1 more source
Nano Select, EarlyView.Polyethylene glycol‐functionalized graphene oxide (PEG‐GO) nanocomposites revolutionize nanomedicine with their high surface area and tunable properties. This review explores their synthesis, characterization, and applications in drug delivery, gene therapy, biosensing, and photothermal therapy.
Oluwasegun Chijioke Adekoya +4 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, EarlyView.ABSTRACT Aficamten is a next‐in‐class, cardiac myosin inhibitor in development as a potential chronic oral treatment for patients with hypertrophic cardiomyopathy (HCM). A population pharmacokinetic (PK) model was developed using data from nine clinical studies to characterize aficamten PK and identify covariates that may alter aficamten exposure ...
Donghong Xu +6 more
wiley +1 more source
A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
Science, 2016 Eric M. Green +18 more
semanticscholar +1 more source
Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration
Small Science, EarlyView.Solvent transfer‐induced phase separation transforms bioinert polyethylene glycol diacrylate into bioactive scaffolds featuring bicontinuous interconnected porosity, with negative Gaussian curvature, and unique topographical patterning. These attributes enable stem cell attachment, proliferation, and differentiation without basement membrane matrix ...
Aihik Banerjee +16 more
wiley +1 more source
The maximum sarcomere length for contraction of isolated myofibrils
, 1964 Richard J. Podolsky
openalex +2 more sources
An mTOR‐Tfeb‐Fabp7a Axis Ameliorates bag3 Cardiomyopathy via Decelerating Cardiac Aging
Aging Cell, EarlyView.This study uncovered accelerated cardiac senescence as a key pathological event in bag3 cardiomyopathy, and reveals that manipulating the mTOR‐Tfeb‐Fabp7a axis can mitigate this pathology and confer cardioprotective effects. ABSTRACT While BAG3 has been identified as a causative gene for dilated cardiomyopathy, the major pathological events in BAG3 ...
Yonghe Ding +7 more
wiley +1 more source