Results 61 to 70 of about 42,993 (322)
Cronos Titin is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function.
Circulation, 2019 Background: The giant sarcomere protein titin is important in both heart health and disease. Mutations in the gene encoding for titin, TTN, are the leading known cause of familial dilated cardiomyopathy.
R. Zaunbrecher +14 more
semanticscholar +1 more source
Redox Signaling and Cardiac Sarcomeres [PDF]
Journal of Biological Chemistry, 2011 Oxidative stress is common in many clinically important cardiac disorders, including ischemia/reperfusion, diabetes, and hypertensive heart disease. Oxidative stress leads to derangements in pump function due to changes in the expression or function of proteins that regulate intracellular Ca(2+) homeostasis.
Marius P, Sumandea, Susan F, Steinberg
openaire +2 more sources
The Space Within: How Architected Voids Promote Tissue Formation
Advanced Materials, EarlyView.This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Chronic high‐dose testosterone treatment: impact on rat cardiac contractile biology
Physiological Reports, 2019 Androgen therapy provides cardiovascular benefits for hypogonadism. However, myocardial hypertrophy, fibrosis, and infarction have been reported in testosterone or androgenic anabolic steroid abuse.
Munthana Wadthaisong +4 more
doaj +1 more source
Sarcomeric dysfunction in heart failure [PDF]
Cardiovascular Research, 2007 Sarcomeric dysfunction plays a central role in reduced cardiac pump function in heart failure. This review focuses on the alterations in sarcomeric proteins in diseased myocardium that range from altered isoform expression to post-translational protein changes such as proteolysis and phosphorylation. Recent studies in animal models of heart failure and
Hamdani, N. +8 more
openaire +4 more sources
Biohybrid Actuators in Compact Arrangement with Embedded X Electrode
Advanced Robotics Research, EarlyView.Selective control of multimuscle biohybrid actuators is crucial for achieving complex movements of biohybrid robots. In this study, embedded X electrodes are fabricated to selectively control multiple muscles, realizing the robotic finger's bidirectional movements.
Tingyu Li, Minghao Nie, Shoji Takeuchi
wiley +1 more source
Advanced Robotics Research, EarlyView.Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin +4 more
wiley +1 more source
Hugh E. Huxley: cambiando el paradigma de la contracción muscular, desde dentro. [Hugh E. Huxley: changing from inside the paradigm of muscle contraction]. [PDF]
Revista Internacional de Ciencias del Deporte, 2014 Desde un punto de vista físico se puede entender la fibra muscular como un motor, es decir, un sistema capaz de transformar la energía química en energía mecánica, que se utiliza para realizar un trabajo.
Adolfo Araci
doaj
Approaches to High-Throughput Analysis of Cardiomyocyte Contractility
Frontiers in Physiology, 2020 The measurement of the contractile behavior of single cardiomyocytes has made a significant contribution to our understanding of the physiology and pathophysiology of the myocardium.
Peter T. Wright +4 more
doaj +1 more source
Childhood Hypertrophic Cardiomyopathy: A Disease of the Cardiac Sarcomere [PDF]
, 2021 Gabrielle Norrish +2 more
openalex +1 more source