Results 11 to 20 of about 16,570 (272)
Active Viscoelasticity of Sarcomeres [PDF]
Frontiers in Robotics and AI, 2018 The perturbation response of muscle is important for the versatile, stable and agile control capabilities of animals. Muscle resists being stretched by developing forces in the passive tissues and in the active crossbridges.
Khoi D. Nguyen +2 more
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Distorting the sarcomere [PDF]
Journal of General Physiology, 2010 One of the goals of cardiovascular science is to create a mathematical model of the heart that can predict ventricular function in healthy and diseased states, and that can be used to help improve treatment options for patients with heart disease. To be clinically useful, the model will have to include structural information about the shapes of the ...
Kenneth S. Campbell
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Sarcomere Length Nonuniformity and Force Regulation in Myofibrils and Sarcomeres [PDF]
Biophysical Journal, 2020 The smallest contractile unit in striated muscles is the sarcomere. Although some of the classic features of contraction assume a uniform behavior of sarcomeres within myofibrils, the occurrence of sarcomere length nonuniformities has been well recognized for years, but it is yet not well understood. In the past years, there has been a great advance in
Felipe de Souza Leite, Dilson E. Rassier
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Spontaneous sarcomere dynamics [PDF]
Chaos: An Interdisciplinary Journal of Nonlinear Science, 2010 Sarcomeres are the basic force generating units of striated muscles and consist of an interdigitating arrangement of actin and myosin filaments. While muscle contraction is usually triggered by neural signals, which eventually set myosin motors into motion, isolated sarcomeres can oscillate spontaneously between a contracted and a relaxed state.
Gunther, Stefan, Kruse, Karsten
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A mathematical model of muscle containing heterogeneous half-sarcomeres exhibits residual force enhancement. [PDF]
PLoS Computational Biology, 2011 A skeletal muscle fiber that is stimulated to contract and then stretched from L₁ to L₂ produces more force after the initial transient decays than if it is stimulated at L₂.
Stuart G Campbell +2 more
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Frontiers in Physiology, 2022 Myofibrillogenesis is an essential process for cardiogenesis and is closely related to excitation-contraction coupling and the maintenance of heartbeat.
Nobutoshi Ichise +9 more
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Rapid IFM Dissection for Visualizing Fluorescently Tagged Sarcomeric Proteins
Bio-Protocol, 2017 Sarcomeres, the smallest contractile unit of muscles, are arguably the most impressive actomyosin structure. Yet a complete understanding of sarcomere formation and maintenance is missing.
Yu Shu Xiao +2 more
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Sarcomere and Inter-Sarcomere Dynamics within Skeletal Muscle Myofibrils [PDF]
Biophysical Journal, 2017 Introduction: Inter-sarcomere dynamics within muscle myofibrils underlie basic mechanisms of contraction. In this study, we used microfluidic perfusions to control the environment of sarcomeres within isolated myofibrils to directly investigate inter-sarcomere dynamics.
Felipe de Souza Leite, Dilson E. Rassier
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Fluid flow in the sarcomere [PDF]
Archives of Biochemistry and Biophysics, 2021 A highly organized and densely packed lattice of molecular machinery within the sarcomeres of muscle cells powers contraction. Although many of the proteins that drive contraction have been studied extensively, the mechanical impact of fluid shearing within the lattice of molecular machinery has received minimal attention. It was recently proposed that
Sage A. Malingen +4 more
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What Can We Learn from Single Sarcomere and Myofibril Preparations?
Frontiers in Physiology, 2022 Sarcomeres are the smallest functional contractile unit of muscle, and myofibrils are striated muscle organelles that are comprised of sarcomeres that are strictly aligned in series.
Walter Herzog
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