Results 191 to 200 of about 79,406 (256)

Natural Synergistic Anti‐Fatigue Formula Development via Zebrafish Model and Combination Index Method

eFood, Volume 7, Issue 2, April 2026.
Red ginseng (RG)–Lycium ruthenicum (LR)–Ganoderma lucidum (GL) compound formula synergistically alleviates fatigue by modulating muscle contraction, enhancing energy metabolism and attenuating oxidative stress. ABSTRACT Many plant and fungal extracts (PFEs) show anti‐fatigue properties through various pathways, but synergistic formulas and mechanisms ...
Tao Liu, Mengmin Li, Fengqin Feng, Yuanxiang Jin, Zhibin Tian, Bokai Wan, Jintao Cheng, Shiyu Li, Qingchi Wang, Chaozhi Wei, Dou Wang, Kan Shao, Ting Luo, Guiling Yang   +13 more
wiley   +1 more source

Wnt/β-catenin pathway induces cardiac dysfunction via AKAP6-mediated RyR2 phosphorylation and sarcoplasmic reticulum calcium leakage. [PDF]

J Mol Cell Biol
Li A, Shen Y, Li Z, Li L.
europepmc   +1 more source

Muscle Weakness and the Irisin–BDNF and Oxidative Stress Axis in the 60‐Day Pseudorandomised Controlled AGBRESA Bed Rest Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 2, April 2026.
ABSTRACT Background Muscle atrophy and weakness are among the most detrimental consequences of disuse, microgravity, hospitalisation and ageing. Oxidative modifications of myofibrillar proteins generated by oxidative stress may contribute to the reduced force‐ and power‐generating capacity of skeletal muscles. As part of the 60‐day AGBRESA bed rest (BR)
Alessandra Bosutti, Bergita Ganse, Edwin Mulder, Markus Gruber, Maria Venegas‐Carro, Jochen Zange, Jörn Rittweger, Moritz Eggelbusch, Rob C. I. Wüst, Paul Hendrickse, Hans Degens   +10 more
wiley   +1 more source

Intercellular NETwork-facilitated sarcoplasmic reticulum targeting for myocardial ischemia-reperfusion injury treatment. [PDF]

Sci Adv
Jiang P, Huang F, Chen L, Zhou H, Deng Y, Li L, Chen M, Huang Y.   +7 more
europepmc   +1 more source

Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia. [PDF]

J Mol Cell Cardiol, 2021
Hamilton S, Terentyeva R, Clements RT, Belevych AE, Terentyev D.   +4 more
europepmc   +1 more source

Prevalence and Mechanisms of Sustained Force Production in the Musculature of the Southern Alligator Lizard (Elgaria multicarinata)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 3, Page 272-281, April 2026.
ABSTRACT The southern alligator lizard (Elgaria multicarinata) exhibits prolonged mate‐holding behavior. This behavior maybe be underpinned by a phenomenon known as sustained force, observed in the jaw muscles of this species, in which the muscle fails to relax between subsequent contractions.
Allyn Nguyen, Kyle Leong, Jessica Phan, Natalie Holt   +3 more
wiley   +1 more source

Blink nadir measurements of sarcoplasmic reticulum are consistent with strong local Ca²⁺ depletion. [PDF]

Biophys J
Gillespie D.
europepmc   +1 more source

Structural basis for sarcolipin's regulation of muscle thermogenesis by the sarcoplasmic reticulum Ca²⁺-ATPase. [PDF]

Sci Adv, 2021
Wang S, Gopinath T, Larsen EK, Weber DK, Walker C, Uddigiri VR, Mote KR, Sahoo SK, Periasamy M, Veglia G.   +9 more
europepmc   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Myofiber structure, sarcoplasmic reticulum Ca²⁺ handling, and contractile function after muscle-damaging exercise in humans. [PDF]

Physiol Rep
Handegard V, Lunde PK, Frisk M, Seynnes O, Ørtenblad N, Louch WE, Paulsen G, Raastad T.   +7 more
europepmc   +1 more source