Results 51 to 60 of about 490,934 (250)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Grado de madurez organizacional en la gestión de proyectos de la empresa Instalaciones Hidráulicas y Sanitarias WC SAS [PDF]
, 2019 Trabajo de InvestigaciónSe presenta el grado de madurez organizacional en la gestión de proyectos para la empresa instalaciones hidráulicas y sanitarias WC SAS , para la gestión de proyectos es importante la estandarización y el óptimo desarrolló de ...
Hurtado-Suesca, Marisol +1 more
core
Conserved molecular interactions in centriole-to-centrosome conversion. [PDF]
, 2015 Centrioles are required to assemble centrosomes for cell division and cilia for motility and signalling. New centrioles assemble perpendicularly to pre-existing ones in G1-S and elongate throughout S and G2.
A Grallert +61 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
An XMM-Newton study of the mixed-morphology supernova remnant W28 (G6.4-0.1) [PDF]
, 2014 We have performed an XMM-Newton imaging and spectroscopic study of supernova remnant (SNR) W28, a prototype mixed-morphology or thermal composite SNR, believed to be interacting with a molecular cloud.
Chen, Yang +5 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Functional Traits of Plant Species Suitable for Revegetation of Landfill Waste from Nickel Smelter
Applied Sciences, 2021 The landfill waste of leached ore residue represents a serious environmental risk and may also negatively affect the appearance, growth and development of vegetation.
Malvína Čierniková +3 more
doaj +1 more source
Coupling form and function: how the oligomerisation symmetry of the SAS-6 protein contributes to the architecture of centriole organelles [PDF]
, 2017 Centrioles make up the centrosome and basal bodies in animals and as such play important roles in cell division, signalling and motility. They possess characteristic 9-fold radial symmetry strongly influenced by the protein SAS-6.
Ford, Jodie +2 more
core +2 more sources
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. [PDF]
, 2018 Centrioles are cylindrical assemblies comprised of 9 singlet, doublet, or triplet microtubules, essential for the formation of motile and sensory cilia.
Agard, David A +3 more
core +1 more source